Chemotherapy‐induced peripheral neuropathy (CIPN) is a common dose‐limiting side effect
experienced by patients receiving treatment for cancer. Approximately 30 to 40% of patients …

Survival rates for most paediatric cancers have improved at a remarkable pace over the past
four decades. In developed countries, cure is now the probable outcome for most children …

Neurotoxic anticancer drugs, such as platinum-based anticancer drugs, taxanes, vinca
alkaloids, and proteasome/angiogenesis inhibitors are responsible for chemotherapy …

Vincristine is a chemotherapeutic agent that is a component of many combination regimens
for a variety of malignancies, including several common pediatric tumors. Vincristine …

Vincristine-induced peripheral neuropathy (VIPN) is a dose-limiting side effect of vincristine
(VCR) treatment in children, leading to diminished quality of life. Much remains unknown …

Purpose Vincristine is widely used as anticancer therapy for a variety of hematological
malignancies. The treatment is limited by progressive vincristine-induced neuropathy …

Precise definition of CIPN clinical features can be obtained by only using validated outcome
measures. Therefore, a major aim of clinical research is to standardize CIPN assessment …

Chemotherapy‐induced peripheral neurotoxicity (CIPN) is a potentially dose‐limiting side
effect of several commonly used cytotoxic chemotherapy agents. The main pharmacological …

Brain cancer and leukemia are the most common cancers diagnosed in the pediatric
population and are often treated with lifesaving chemotherapy. However, chemotherapy …

Importance In light of the excellent long-term survival of childhood cancer patients, it is
imperative to screen for factors affecting health, function, and quality of life in long-term …