Thermoresponsive in situ gel of curcumin loaded solid lipid nanoparticle: design, optimization and in vitro characterization

M Agrawal, M Pradhan, G Singhvi, R Patel… - Journal of Drug Delivery …, 2022 - Elsevier
Owing to the antioxidant, anti-inflammatory, amyloid inhibition, and neuroprotective potency,
curcumin proved as an excellent herbal bioactive to treat AD. However, poor solubility …

Central composite design implemented azilsartan medoxomil loaded nanoemulsion to improve its aqueous solubility and intestinal permeability: in vitro and ex vivo …

G Kumar, T Virmani, K Pathak, OA Kamaly, A Saleh - Pharmaceuticals, 2022 - mdpi.com
The present research attempted to design and develop a nanoemulsion formulation of
azilsartan medoxomil to improve its aqueous solubility and intestinal permeability. Based on …

An update on nanoparticle formulation design of piperine to improve its oral bioavailability: a review

AK Nugroho, N Kusumorini… - Iraqi Journal of …, 2023 - bijps.uobaghdad.edu.iq
Piperine, a crystalline alkaloid compound isolated from Piper nigrum, piper longum, and
other types of piper, has had many fabulous pharmacological advantages for preventing and …

Formulation of self-nanoemulsifying drug delivery system of cephalexin: physiochemical characterization and antibacterial evaluation

A Zafar, M Yasir, NK Alruwaili, SS Imam, OA Alsaidan… - Polymers, 2022 - mdpi.com
A cephalexin (CEP) self-nanoemulsifying drug delivery system (SNEDDS) was developed in
this study to improve the drug's oral administration. The CEP-SNEDDS was made utilizing …

Amorphous System of Hesperetin and Piperine—Improvement of Apparent Solubility, Permeability, and Biological Activities

K Wdowiak, A Miklaszewski, R Pietrzak… - International Journal of …, 2023 - mdpi.com
The low bioaccessibility of hesperetin and piperine hampers their application as therapeutic
agents. Piperine has the ability to improve the bioavailability of many compounds when co …

Development of piperine nanoemulsions: An alternative topical application for hypopigmentation

B Ozkan, E Altuntas, R Cakir Koc… - Drug development and …, 2022 - Taylor & Francis
This study, it was aimed to develop a topical piperine nanoemulsion (P-NE) using an
ultrasonic emulsification process to find an alternative treatment option for some …

Submicron polymer particles loaded with piperine: Preparation from fucoidan and evaluation of morphology, release profile, and antioxidant activity

EO Mensah, ET Bulya, AS Minin, MA Mironov - Food Hydrocolloids, 2023 - Elsevier
A combination of two methods, polyelectrolyte self-assembly of fucoidan–chitosan and
isocyanide-based multicomponent reactions, was used to obtain submicron polymer …

Reduced the food effect and enhanced the oral bioavailability of ivacaftor by self-nanoemulsifying drug delivery system (SNEDDS) using a new oil phase

Y Miao, S Zhao, J Zuo, J Sun… - Drug Design, Development …, 2022 - Taylor & Francis
Purpose The purpose of this work was to develop an ivacaftor self-nanoemulsion drug
delivery system (IVA-SNEDDS) using the newly developed double headed miscellaneous …

[HTML][HTML] Design and dermatokinetic appraisal of lornoxicam-loaded ultrafine self-nanoemulsion hydrogel for the management of inflammation: In vitro and in vivo …

SA Al-Suwayeh, MM Badran, GO Alhumoud… - Saudi Pharmaceutical …, 2023 - Elsevier
The present study aimed to evaluate the impact of ultrafine nanoemulsions on the
transdermal delivery of lornoxicam (LOR) for management of the inflammation. The …

Multi-functional chitosan copolymer modified nanocrystals as oral andrographolide delivery systems for enhanced bioavailability and anti-inflammatory efficacy

W Liu, M Cheng, Z Lu, H Li, Y Feng, Y Jin, S Yang… - Drug Delivery, 2022 - Taylor & Francis
Modifying nanocrystals with functional materials have been common strategy to enlarge the
enhancing ability on oral absorption via nanocrystals; however, whether the functional …