Background Kisspeptin is the leading upstream regulator of pulsatile and surge
Gonadotrophin-Releasing Hormone secretion (GnRH) in the hypothalamus, which acts as …

Abstract Infertility affects 1-in-6 couples, with repeated intensive cycles of assisted
reproductive technology (ART) required by many to achieve a desired live birth. In ART …

BACKGROUND Kisspeptin is a key regulator of hypothalamic gonadotropin-releasing
hormone (GnRH) neurons and is essential for reproductive health. A specific kisspeptin …

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of
reproductive age and is the leading cause of anovulatory subfertility. Increased …

The POSEIDON group (P atient-O riented S trategies E ncompassing I ndividualize DO ocyte
N umber) has introduced “the ability to retrieve the number of oocytes needed to achieve at …

Infertility affects one in six couples, with in vitro fertilization (IVF) offering many the chance of
conception. Compared to the solitary oocyte produced during the natural menstrual cycle …

Follicle-stimulating hormone (FSH) promotes the production and secretion of estrogen,
which in turn stimulates the growth and maturation of ovarian follicles. Therefore …

Introduction For high responders with polycystic ovary syndrome (PCOS), there is no clear
recommendation for the initial follicle-stimulating hormone (FSH) dosage to ensure an …

Context Osteoporosis results from disturbances in bone formation and resorption. Recent
nonhuman data suggest that the reproductive hormone kisspeptin directly stimulates …

A primary reason behind the high level of complexity we embody as multicellular organisms
is a highly complex intracellular and intercellular communication system. As a result, the …