Regulation of ribosomal proteins on viral infection

S Li - Cells, 2019 - mdpi.com
Ribosomal proteins (RPs), in conjunction with rRNA, are major components of ribosomes
involved in the cellular process of protein biosynthesis, known as “translation”. The viruses …

Who regulates whom? An overview of RNA granules and viral infections

N Poblete-Durán, Y Prades-Pérez, J Vera-Otarola… - Viruses, 2016 - mdpi.com
After viral infection, host cells respond by mounting an anti-viral stress response in order to
create a hostile atmosphere for viral replication, leading to the shut-off of mRNA translation …

Bioinformatics analyses of significant genes, related pathways, and candidate diagnostic biomarkers and molecular targets in SARS-CoV-2/COVID-19

B Vastrad, C Vastrad, A Tengli - Gene Reports, 2020 - Elsevier
Severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) infection is a leading
cause of pneumonia and death. The aim of this investigation is to identify the key genes in …

SARS-CoV-2 nucleocapsid protein is a potential therapeutic target for anticoronavirus drug discovery

A Royster, S Ren, Y Ma, M Pintado, E Kahng… - Microbiology …, 2023 - Am Soc Microbiol
ABSTRACT SARS-CoV-2, the etiologic agent of the COVID-19 pandemic, is a highly
contagious positive-sense RNA virus. Its explosive community spread and the emergence of …

Hantaviruses use the endogenous host factor P58IPK to combat the PKR antiviral response

Z Wang, S Ren, Q Li, AD Royster, L Lin, S Liu… - PLoS …, 2021 - journals.plos.org
Hantavirus nucleocapsid protein (NP) inhibits protein kinase R (PKR) dimerization by an
unknown mechanism to counteract its antiviral responses during virus infection. Here we …

Amplicon-Based, Next-Generation Sequencing Approaches to Characterize Single Nucleotide Polymorphisms of Orthohantavirus Species

MK Taylor, EP Williams, T Wongsurawat… - Frontiers in Cellular …, 2020 - frontiersin.org
Whole-genome sequencing (WGS) of viruses from patient or environmental samples can
provide tremendous insight into the epidemiology, drug resistance or evolution of a virus …

The nucleocapsid protein of hantaviruses: much more than a genome-wrapping protein

M Reuter, DH Krüger - Virus Genes, 2018 - Springer
The nucleocapsid (N) protein of hantaviruses represents an impressive example of a viral
multifunctional protein. It encompasses properties as diverse as genome packaging, RNA …

[HTML][HTML] Phosphorylated STAT5 directly facilitates parvovirus B19 DNA replication in human erythroid progenitors through interaction with the MCM complex

SS Ganaie, W Zou, P Xu, X Deng, S Kleiboeker… - PLoS …, 2017 - journals.plos.org
Productive infection of human parvovirus B19 (B19V) exhibits high tropism for burst forming
unit erythroid (BFU-E) and colony forming unit erythroid (CFU-E) progenitor cells in human …

Structure of the hantavirus nucleoprotein provides insights into the mechanism of RNA encapsidation

D Olal, O Daumke - Cell Reports, 2016 - cell.com
Hantaviruses are etiological agents of life-threatening hemorrhagic fever with renal
syndrome and hantavirus cardiopulmonary syndrome. The nucleoprotein (N) of hantavirus is …

A novel compound targets the feline infectious peritonitis virus nucleocapsid protein and inhibits viral replication in cell culture

N Mohseni, A Royster, S Ren, Y Ma, M Pintado… - Journal of Biological …, 2023 - ASBMB
Feline infectious peritonitis (FIP) is a serious viral illness in cats, caused by feline
coronavirus. Once a cat develops clinical FIP, the prognosis is poor. The effective treatment …