AMPA receptors (AMPARs) are assemblies of four core subunits, GluA1–4, that mediate
most fast excitatory neurotransmission. The component subunits determine the functional …

The postsynaptic side of the synapse is specialized to receive the neurotransmitter signal
released from the presynaptic terminal and transduce it into electrical and biochemical …

Even in healthy individuals there is an inexorable agerelated decline in cognitive function.
This is due, in large part, to reduced synaptic plasticity caused by changes in the molecular …

Cadherins are Ca2+-dependent cell-cell adhesion molecules that play critical roles in
animal morphogenesis. Various cadherin-related molecules have also been identified …

Autoimmune synaptic encephalitides are recently described human brain diseases leading
to psychiatric and neurological syndromes through inappropriate brain–autoantibody …

INTRODUCTION Mutations of the X-linked Protocadherin-19 (PCDH19) gene cause
PCDH19 disorder with epilepsy. PCDH19 disorder is often associated with cognitive …

The role of glia in modulating neuronal network activity is an important question.
Oligodendrocyte precursor cells (OPC) characteristically express the transmembrane …

NMDA receptors are found in neurons both at synapses and in extrasynaptic locations.
Extrasynaptic locations are poorly characterized. Here we used preembedding …

Dendritic spines are postsynaptic compartments of excitatory synapses that undergo
dynamic changes during development, including rapid spinogenesis in early postnatal life …

The storage of information in the mammalian nervous systems is dependent on a delicate
balance between change and stability of neuronal networks. The induction and …