Channelopathies in fragile X syndrome
PY Deng, VA Klyachko - Nature Reviews Neuroscience, 2021 - nature.com
Fragile X syndrome (FXS) is the most common inherited form of intellectual disability and the
leading monogenic cause of autism. The condition stems from loss of fragile X mental …
leading monogenic cause of autism. The condition stems from loss of fragile X mental …
Early intervention in neurodevelopmental disorders: underlying neural mechanisms
G Cioni, E Inguaggiato… - … medicine & child …, 2016 - Wiley Online Library
Neurodevelopmental disorders affect motor, cognitive, language, learning, and behavioural
development with lifelong consequences. Early identification of infants at risk for …
development with lifelong consequences. Early identification of infants at risk for …
Mouse and rat ultrasonic vocalizations in neuroscience and neuropharmacology: State of the art and future applications
M Premoli, S Pietropaolo, M Wöhr… - European Journal of …, 2023 - Wiley Online Library
Mice and rats emit ultrasonic vocalizations (USVs), which may express their arousal and
emotional states, to communicate with each other. There is continued scientific effort to …
emotional states, to communicate with each other. There is continued scientific effort to …
Differential effects of social and physical environmental enrichment on brain plasticity, cognition, and ultrasonic communication in rats
JC Brenes, M Lackinger, GU Höglinger… - Journal of …, 2016 - Wiley Online Library
Environmental enrichment (EE) exerts beneficial effects on brain plasticity, cognition, and
anxiety/depression, leading to a brain that can counteract deficits underlying various brain …
anxiety/depression, leading to a brain that can counteract deficits underlying various brain …
Enriched environments as a potential treatment for developmental disorders: a critical assessment
NJ Ball, E Mercado III, I Orduña - Frontiers in psychology, 2019 - frontiersin.org
The beneficial effects of enriched environments have been established through a long
history of research. Enrichment of the living conditions of captive animals in the form of …
history of research. Enrichment of the living conditions of captive animals in the form of …
Environmental enrichment as a positive behavioral intervention across the lifespan
P Sampedro-Piquero, A Begega - Current neuropharmacology, 2017 - ingentaconnect.com
Background: In recent decades, the interest in behavioral interventions has been growing
due to the higher prevalence of age-related cognitive impairments. Hence, behavioral …
due to the higher prevalence of age-related cognitive impairments. Hence, behavioral …
Genetic and non-genetic animal models for autism spectrum disorders (ASD)
Z Ergaz, L Weinstein-Fudim, A Ornoy - Reproductive Toxicology, 2016 - Elsevier
Autism spectrum disorder (ASD) is associated, in addition to complex genetic factors, with a
variety of prenatal, perinatal and postnatal etiologies. We discuss the known animal models …
variety of prenatal, perinatal and postnatal etiologies. We discuss the known animal models …
Environmental enrichment attenuates behavioral abnormalities in valproic acid-exposed autism model mice
We recently demonstrated that prenatal exposure to valproic acid (VPA) at embryonic day
12.5 causes autism spectrum disorder (ASD)-like phenotypes such as hypolocomotion …
12.5 causes autism spectrum disorder (ASD)-like phenotypes such as hypolocomotion …
[HTML][HTML] Therapeutic strategies in fragile X syndrome: from bench to bedside and back
Fragile X syndrome (FXS), an inherited intellectual disability often associated with autism, is
caused by the loss of expression of the fragile X mental retardation protein. Tremendous …
caused by the loss of expression of the fragile X mental retardation protein. Tremendous …
Autistic-like behavioral effects of prenatal stress in juvenile Fmr1 mice: the relevance of sex differences and gene–environment interactions
Abstract Fragile X Syndrome (FXS) is the most common heritable form of mental retardation
and monogenic cause of autism spectrum disorder (ASD). FXS is due to a mutation in the X …
and monogenic cause of autism spectrum disorder (ASD). FXS is due to a mutation in the X …