Muscular dystrophies and congenital myopathies arise from specific genetic mutations
causing skeletal muscle weakness that reduces quality of life. Muscle health relies on …

Duchenne muscular dystrophy (DMD) is a severe and progressive myopathy leading to
motor and cardiorespiratory impairment. We analyzed samples from patients with DMD and …

Cu (Cu) is essential for several biochemical pathways due to its role as a catalytic cofactor or
allosteric regulator of enzymes. Its import and distribution are tightly controlled by …

Development is regulated by various factors, including protein methylation status. While
PRMT5 is well known for its roles in oncogenesis by mediating symmetric di-methylation of …

Myofibers are the main components of skeletal muscle, which is the largest tissue in the
body. Myofibers are highly adaptive and can be altered under different biological and …

Muscle stem cells (MuSCs) enable muscle growth and regeneration after exercise or injury,
but how metabolism controls their regenerative potential is poorly understood. We describe …

Multinucleated skeletal muscle cells have an obligatory need to acquire additional nuclei
through fusion with activated skeletal muscle stem cells when responding to both …

Previous studies have shown that vitamin C (VC), an essential vitamin for the human body,
can promote the differentiation of muscle satellite cells (MuSCs) in vitro and play an …

Three-dimensional tissue-engineered models are poised to facilitate progress in
understanding skeletal muscle pathophysiology and identify novel therapeutic agents to …

Musculoskeletal dysfunction is an age-related syndrome associated with impaired
mitochondrial function and proteostasis. However, few interventions have tested targeting …