[HTML][HTML] Defining and identifying satellite cell-opathies within muscular dystrophies and myopathies
M Ganassi, F Muntoni, PS Zammit - Experimental Cell Research, 2022 - Elsevier
Muscular dystrophies and congenital myopathies arise from specific genetic mutations
causing skeletal muscle weakness that reduces quality of life. Muscle health relies on …
causing skeletal muscle weakness that reduces quality of life. Muscle health relies on …
Thyroid-stimulating hormone receptor signaling restores skeletal muscle stem cell regeneration in rats with muscular dystrophy
V Taglietti, K Kefi, L Rivera, O Bergiers… - Science Translational …, 2023 - science.org
Duchenne muscular dystrophy (DMD) is a severe and progressive myopathy leading to
motor and cardiorespiratory impairment. We analyzed samples from patients with DMD and …
motor and cardiorespiratory impairment. We analyzed samples from patients with DMD and …
Regulation of Atp7a RNA contributes to differentiation-dependent Cu redistribution in skeletal muscle cells
TJ Whitlow, Y Zhang, N Ferguson, AM Perez… - Metallomics, 2023 - academic.oup.com
Cu (Cu) is essential for several biochemical pathways due to its role as a catalytic cofactor or
allosteric regulator of enzymes. Its import and distribution are tightly controlled by …
allosteric regulator of enzymes. Its import and distribution are tightly controlled by …
[HTML][HTML] PRMT5 mediates FoxO1 methylation and subcellular localization to regulate lipophagy in myogenic progenitors
Development is regulated by various factors, including protein methylation status. While
PRMT5 is well known for its roles in oncogenesis by mediating symmetric di-methylation of …
PRMT5 is well known for its roles in oncogenesis by mediating symmetric di-methylation of …
Application of ATAC-Seq for genome-wide analysis of the chromatin state at single myofiber resolution
K Sahinyan, DM Blackburn, MM Simon, F Lazure… - Elife, 2022 - elifesciences.org
Myofibers are the main components of skeletal muscle, which is the largest tissue in the
body. Myofibers are highly adaptive and can be altered under different biological and …
body. Myofibers are highly adaptive and can be altered under different biological and …
[HTML][HTML] GLUD1 determines murine muscle stem cell fate by controlling mitochondrial glutamate levels
Muscle stem cells (MuSCs) enable muscle growth and regeneration after exercise or injury,
but how metabolism controls their regenerative potential is poorly understood. We describe …
but how metabolism controls their regenerative potential is poorly understood. We describe …
[HTML][HTML] Lineage tracing of newly accrued nuclei in skeletal myofibers uncovers distinct transcripts and interplay between nuclear populations
C Sun, CO Swoboda, MJ Petrany, S Parameswaran… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Multinucleated skeletal muscle cells have an obligatory need to acquire additional nuclei
through fusion with activated skeletal muscle stem cells when responding to both …
through fusion with activated skeletal muscle stem cells when responding to both …
Vitamin C regulates skeletal muscle post-injury regeneration by promoting myoblast proliferation through its direct interaction with the Pax7 protein
X Zhang, B Tian, H Yu, S Li, S Li, J Su, H Tong - Food & Function, 2024 - pubs.rsc.org
Previous studies have shown that vitamin C (VC), an essential vitamin for the human body,
can promote the differentiation of muscle satellite cells (MuSCs) in vitro and play an …
can promote the differentiation of muscle satellite cells (MuSCs) in vitro and play an …
Cryopreservation of myoblasts in paper-based scaffolds for inter-laboratory studies of skeletal muscle health
SSTH Rjaibi - 2023 - search.proquest.com
Three-dimensional tissue-engineered models are poised to facilitate progress in
understanding skeletal muscle pathophysiology and identify novel therapeutic agents to …
understanding skeletal muscle pathophysiology and identify novel therapeutic agents to …
Phytochemical Nrf2 activator attenuates skeletal muscle mitochondrial dysfunction and impaired proteostasis in a preclinical model of musculoskeletal aging
Musculoskeletal dysfunction is an age-related syndrome associated with impaired
mitochondrial function and proteostasis. However, few interventions have tested targeting …
mitochondrial function and proteostasis. However, few interventions have tested targeting …