Heart transplantation has become a standard therapy option for advanced heart failure. The
translation of heart transplantation from innovative experiments to long-term clinical success …

Endomyocardial biopsy (EMB) is an invasive procedure originally developed for the
monitoring of heart transplant rejection. Over the year, this procedure has gained a …

Background: After heart transplantation, endomyocardial biopsy (EMBx) is used to monitor
for acute rejection (AR). Unfortunately, EMBx is invasive, and its conventional histological …

Background Given the shortage of suitable donor hearts for cardiac transplantation and the
growing interest in donation after circulatory death (DCD), our institution recently began …

Human embryonic stem cell-derived cardiomyocytes (hESC-CMs) show considerable
promise for regenerating injured hearts, and we therefore tested their capacity to stably …

The Registry of the International Society for Heart and Lung Transplantation: Thirty-second
Official Adult Heart Transplantation Report--2015; Focus Theme: Early Graft Failure. - Abstract …

An obstacle to cancer immunotherapy has been that the affinity of T-cell receptors (TCRs) for
antigens expressed in tumors is generally low. We initiated clinical testing of engineered T …

Data are submitted to the International Society for Heart and Lung Transplantation (ISHLT)
Registry by national and multinational organ and data exchange organizations or by …

Summary Background The Organ Care System is the only clinical platform for ex-vivo
perfusion of human donor hearts. The system preserves the donor heart in a warm beating …

Monitoring allograft health is an important component of posttransplant therapy.
Endomyocardial biopsy is the current gold standard for cardiac allograft monitoring but is an …