Ischemia and reperfusion (I/R) causes a reduction in arterial blood supply to tissues,
followed by the restoration of perfusion and consequent reoxygenation. The reestablishment …

Cancer is the second leading cause of death after cardiovascular diseases. Conventional
anticancer therapies are associated with lack of selectivity and serious side effects. Cancer …

Cancer is one of the main causes of death globally and considered as a major challenge for
the public health system. The high toxicity and the lack of selectivity of conventional …

Oxidative stress, caused by extreme accumulation of un-scavenged reactive oxygen
species, plays an integral role in the Ischemia-Reperfusion (I/R) injury to the testicles …

Background: Doxorubicin (DOX) is used for treatment of many cancer types. Thymoquinone
(THQ) is a powerful antioxidant agent used for reducing side effects of several drugs. The …

Objectives: In this experimental study, a testicular torsion/detorsion model was used in male
rats to investigate the effect of onion juice on male fertility factors and rate of pregnancy by …

Testicular torsion or torsion of the spermatic cord is one of the most serious urological
conditions. It causes testicular injury, which potentially leads to male subfertility. The turning …

Objective This study used a rat model to investigate the protective effect of tadalafil and
verapamil on testicular function and oxidative stress after torsion/detorsion. Methods and …

Testicular torsion-detorsion results in enhanced formation of free radicals which contribute to
the pathophysiology of testicular tissue damage. Recent reports have identified protective …

Background Testicular torsion is a condition in which a testis rotates around its longitudinal
axis and twists the spermatic cord. This in turn results in a significant decrease in blood flow …