The degree of frailty as a translational measure of health in aging
Frailty is a multiply determined, age-related state of increased risk for adverse health
outcomes. We review how the degree of frailty conditions the development of late-life …
outcomes. We review how the degree of frailty conditions the development of late-life …
Frailty-aware care: giving value to frailty assessment across different healthcare settings
Healthcare systems need to adapt to better serve an aging population with complex
presentations. Frailty assessments are a potential means to address this heterogeneity in …
presentations. Frailty assessments are a potential means to address this heterogeneity in …
Screening for and managing the person with frailty in primary care: ICFSR consensus guidelines
1. Geriatric Medicine, University of Miami Miller School of Medicine, Miami, Florida, USA; 2.
Torrens University of Australia, Adelaide and Baker Heart and Diabetes Institute, Melbourne …
Torrens University of Australia, Adelaide and Baker Heart and Diabetes Institute, Melbourne …
Changes in the severity and lethality of age-related health deficit accumulation in the USA between 1999 and 2018: a population-based cohort study
Background With an ageing population, the number of people with frailty is increasing.
Despite this trend, the extent to which the severity and lethality of frailty have changed over …
Despite this trend, the extent to which the severity and lethality of frailty have changed over …
Epigenetic age is associated with baseline and 3-year change in frailty in the Canadian Longitudinal Study on Aging
Background The trajectory of frailty in older adults is important to public health; therefore,
markers that may help predict this and other important outcomes could be beneficial …
markers that may help predict this and other important outcomes could be beneficial …
How to construct a frailty index from an existing dataset in 10 steps
Background The frailty index is commonly used in research and clinical practice to quantify
health. Using a health deficit accumulation model, a frailty index can be calculated …
health. Using a health deficit accumulation model, a frailty index can be calculated …
Frailty assessment for COVID-19 follow-up: a prospective cohort study
I Müller, M Mancinetti, A Renner… - BMJ open …, 2022 - bmjopenrespres.bmj.com
Background The Clinical Frailty Scale (CFS) is increasingly used for clinical decision making
in acute care but little is known about frailty after COVID-19. Objectives To investigate frailty …
in acute care but little is known about frailty after COVID-19. Objectives To investigate frailty …
Post-intensive care syndrome follow-up system after hospital discharge: a narrative review
N Nakanishi, K Liu, J Hatakeyama, A Kawauchi… - Journal of Intensive …, 2024 - Springer
Background Post-intensive care syndrome (PICS) is the long-lasting impairment of physical
functions, cognitive functions, and mental health after intensive care. Although a long-term …
functions, cognitive functions, and mental health after intensive care. Although a long-term …
Associations of adverse childhood experiences with frailty in older adults: a cross-sectional analysis of data from the Canadian Longitudinal Study on Aging
Introduction: Frailty in older adults, characterized by a decline in multiple physiological
systems and increasing vulnerability to loss of independence, disability, and death, is a …
systems and increasing vulnerability to loss of independence, disability, and death, is a …
A DNA methylation based measure outperforms circulating CRP as a marker of chronic inflammation and partly reflects the monocytic response to long‐term …
A key hallmark in the age‐related dysfunction of physiological systems is disruption related
to the regulation of inflammation, often resulting in a chronic, low‐grade inflammatory state …
to the regulation of inflammation, often resulting in a chronic, low‐grade inflammatory state …