Traditional Chinese medicine network pharmacology: theory, methodology and application
LI Shao, B Zhang - Chinese journal of natural medicines, 2013 - Elsevier
Traditional Chinese medicine (TCM) has a long history of viewing an individual or patient as
a system with different statuses, and has accumulated numerous herbal formulae. The …
a system with different statuses, and has accumulated numerous herbal formulae. The …
Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive review
P Csermely, T Korcsmáros, HJM Kiss, G London… - Pharmacology & …, 2013 - Elsevier
Despite considerable progress in genome-and proteome-based high-throughput screening
methods and in rational drug design, the increase in approved drugs in the past decade did …
methods and in rational drug design, the increase in approved drugs in the past decade did …
AnimalTFDB 4.0: a comprehensive animal transcription factor database updated with variation and expression annotations
WK Shen, SY Chen, ZQ Gan, YZ Zhang… - Nucleic acids …, 2023 - academic.oup.com
Transcription factors (TFs) are proteins that interact with specific DNA sequences to regulate
gene expression and play crucial roles in all kinds of biological processes. To keep up with …
gene expression and play crucial roles in all kinds of biological processes. To keep up with …
Mass-spectrometry-based draft of the Arabidopsis proteome
Plants are essential for life and are extremely diverse organisms with unique molecular
capabilities. Here we present a quantitative atlas of the transcriptomes, proteomes and …
capabilities. Here we present a quantitative atlas of the transcriptomes, proteomes and …
STRING v9. 1: protein-protein interaction networks, with increased coverage and integration
A Franceschini, D Szklarczyk, S Frankild… - Nucleic acids …, 2012 - academic.oup.com
Complete knowledge of all direct and indirect interactions between proteins in a given cell
would represent an important milestone towards a comprehensive description of cellular …
would represent an important milestone towards a comprehensive description of cellular …
[HTML][HTML] Graph embedding and Gaussian mixture variational autoencoder network for end-to-end analysis of single-cell RNA sequencing data
Single-cell RNA sequencing (scRNA-seq) is a revolutionary technology to determine the
precise gene expression of individual cells and identify cell heterogeneity and …
precise gene expression of individual cells and identify cell heterogeneity and …
[HTML][HTML] The roles of post-translational modifications in the context of protein interaction networks
Among other effects, post-translational modifications (PTMs) have been shown to exert their
function via the modulation of protein-protein interactions. For twelve different main PTM …
function via the modulation of protein-protein interactions. For twelve different main PTM …
dbPTM in 2019: exploring disease association and cross-talk of post-translational modifications
Abstract The dbPTM (http://dbPTM. mbc. nctu. edu. tw/) has been maintained for over 10
years with the aim to provide functional and structural analyses for post-translational …
years with the aim to provide functional and structural analyses for post-translational …
Characterizing the genetic basis of transcriptome diversity through RNA-sequencing of 922 individuals
Understanding the consequences of regulatory variation in the human genome remains a
major challenge, with important implications for understanding gene regulation and …
major challenge, with important implications for understanding gene regulation and …
Biological network exploration with Cytoscape 3
Cytoscape is one of the most popular open‐source software tools for the visual exploration
of biomedical networks composed of protein, gene, and other types of interactions. It offers …
of biomedical networks composed of protein, gene, and other types of interactions. It offers …