Glycosylation is one of the most prevalent posttranslational modifications that profoundly
affects the structure and functions of proteins in a wide variety of biological recognition …

A robust platform for facile defined glycan synthesis does not exist. Yet the need for such
technology has never been greater as researchers seek to understand the full scope of …

Glycosylation can significantly improve the physicochemical and biological properties of
small molecules like vitamins, antibiotics, flavors, and fragrances. The chemical synthesis of …

Human milk oligosaccharides (HMOs) signify a unique group of oligosaccharides in breast
milk, which is of major importance for infant health and development. The functional benefits …

The many advances in glycoscience have more and more brought to light the crucial role of
glycosides and glycoconjugates in biological processes. Their major influence on the …

This review is the sixth update of the original article published in 1999 on the application of
MALDI mass spectrometry to the analysis of carbohydrates and glycoconjugates and brings …

Recently, significant progress has been made within enzymatic synthesis of biomimetic,
functional glycans, including, for example, human milk oligosaccharides. These compounds …

Fucosylation is important for the function of many proteins with biotechnical and medical
applications. Alpha-fucosidases comprise a large enzyme family that recognizes fucosylated …

Diglycosidases are a special class of glycosidases (EC 3.2. 1) that catalyze the separation of
intact disaccharide moieties from the aglycone part. The main diglycosidase representatives …

α-l-Fucosyl residues attached at the non-reducing ends of glycoconjugates constitute histo-
blood group antigens Lewis (Le) and ABO and play fundamental roles in various biological …