Molecular photoswitches in aqueous environments

J Volarić, W Szymanski, NA Simeth… - Chemical Society …, 2021 - pubs.rsc.org
Molecular photoswitches enable dynamic control of processes with high spatiotemporal
precision, using light as external stimulus, and hence are ideal tools for different research …

Photoswitchable diarylethenes: from molecular structures to biological applications

Z Li, X Zeng, C Gao, J Song, F He, T He, H Guo… - Coordination Chemistry …, 2023 - Elsevier
Diarylethene (DAE) photoswitches, known for their reversible photoinduced cyclization and
cycloreversion reactions, have shown great promise in various fields such as optical data …

Proline Analogues

V Kubyshkin, M Rubini - Chemical Reviews, 2024 - ACS Publications
Within the canonical repertoire of the amino acid involved in protein biogenesis, proline
plays a unique role as an amino acid presenting a modified backbone rather than a side …

Photoswitchable peptides for spatiotemporal control of biological functions

L Albert, O Vázquez - Chemical Communications, 2019 - pubs.rsc.org
Light is unsurpassed in its ability to modulate biological interactions. Since their discovery,
chemists have been fascinated by photosensitive molecules capable of switching between …

Data-mining unveils structure–property–activity correlation of viral infectivity enhancing self-assembling peptides

K Kaygisiz, L Rauch-Wirth, A Dutta, X Yu… - Nature …, 2023 - nature.com
Gene therapy via retroviral vectors holds great promise for treating a variety of serious
diseases. It requires the use of additives to boost infectivity. Amyloid-like peptide nanofibers …

How do donor and acceptor substituents change the photophysical and photochemical behavior of dithienylethenes? The search for a water-soluble visible-light …

S Qiu, AT Frawley, KG Leslie, HL Anderson - Chemical Science, 2023 - pubs.rsc.org
Dithienylethenes are a type of diarylethene and they constitute one of the most widely
studied classes of photoswitch, yet there have been no systematic studies of how electron …

Recent advances in the exploration of therapeutic analogues of gramicidin S, an old but still potent antimicrobial peptide

Q Guan, S Huang, Y Jin, R Campagne… - Journal of medicinal …, 2019 - ACS Publications
Gramicidin S (GS), one of the oldest commercially used peptide antibiotics, is known for its
robust antibacterial activity against both Gram-positive and Gram-negative bacterial strains …

Rediscovery of antimicrobial peptides as therapeutic agents

M Ryu, J Park, JH Yeom, M Joo, K Lee - Journal of Microbiology, 2021 - Springer
In recent years, the occurrence of antibiotic-resistant pathogens is increasing rapidly. There
is growing concern as the development of antibiotics is slower than the increase in the …

[HTML][HTML] Photoswitching of model ion channels in lipid bilayers

J Pfeffermann, B Eicher, D Boytsov… - … of Photochemistry and …, 2021 - Elsevier
Membrane proteins can be regulated by alterations in material properties intrinsic to the
hosting lipid bilayer. Here, we investigated whether the reversible photoisomerization of …

β-Turn editing in Gramicidin S: Activity impact on replacing proline α-carbon with stereodynamic nitrogen

J Lal, G Kaul, A Akhir, D Saxena, H Dubkara… - Bioorganic …, 2023 - Elsevier
Gramicidin S, natural antimicrobial peptide is used commercially in medicinal lozenges for
sore throat and Gram-negative and Gram-positive bacterial infections. However, its clinical …