Role of Efflux Pumps on Antimicrobial Resistance in Pseudomonas aeruginosa

AB Lorusso, JA Carrara, CDN Barroso, FF Tuon… - International journal of …, 2022 - mdpi.com
Antimicrobial resistance is an old and silent pandemic. Resistant organisms emerge in
parallel with new antibiotics, leading to a major global public health crisis over time …

Efflux in Gram-negative bacteria: what are the latest opportunities for drug discovery?

T Gil-Gil, P Laborda, LE Ochoa-Sánchez… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction The resistance-nodulation-division (RND) family is the most important group of
multidrug efflux pumps in Gram-negative bacteria. Their inhibition increases the …

Metagenome meta-analysis reveals an increase in the abundance of some multidrug efflux pumps and mobile genetic elements in chemically polluted environments

J Subirats, H Sharpe, V Tai, M Fruci… - Applied and …, 2023 - Am Soc Microbiol
Many human activities contaminate terrestrial and aquatic environments with numerous
chemical pollutants that not only directly alter the environment but also affect microbial …

Heat-killed Lactobacillus rhamnosus GG with different cultivation time restores intestinal epithelial barrier dysfunction via MLCK/MLC pathway activation

Z Xie, Y Wang, L Du, X Wu, R Liu, S Li, Q Wang… - Food Bioscience, 2024 - Elsevier
Heat-killed Lactobacillus rhamnosus GG (HK-LGG) has been proven to improve intestinal
health, boost immunity, and exert anti-tumor effects. However, the effect of LGG with different …

Mutation Analysis in Regulator DNA-Binding Regions for Antimicrobial Efflux Pumps in 17,000 Pseudomonas aeruginosa Genomes

M Pérez-Vázquez, C López-Causapé, A Corral-Lugo… - Microorganisms, 2023 - mdpi.com
Mutations leading to upregulation of efflux pumps can produce multiple drug resistance in
the pathogen Pseudomonas aeruginosa. Changes in their DNA binding regions, ie …

[HTML][HTML] Resistome Signature and Antibiotic Resistance Mechanisms in Rhizospheric Soil Bacteriomes of Mecca Region, Saudi Arabia: Insights into Impact on Human …

RS Jalal, HS Sonbol - Life, 2024 - pmc.ncbi.nlm.nih.gov
The objective of this investigation is to ascertain the distinctive profile of the rhizospheric soil
resistome within the Mecca region, while also evaluating the potential risks associated with …

[HTML][HTML] Fuzheng Touxie Jiedu Huayu Decoction inhibits the MexAB-OprM efflux pump and Quorum Sensing-mediated biofilm formation in difficult-to-treat multidrug …

T Liu, H Xu, T Huang, G Liu, H Cao, Y Lin, Y Li… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Fuzheng Touxie Jiedu Huayu Decoction (FTJHD)
is a commonly used clinical formula that has been found effective in resisting multidrug …

[PDF][PDF] Food Bioscience

H Tie, J Dong, Q Jiang, D Yu, F Yang, Y Xu, W Xia - researchgate.net
Flesh quality changes during postmortem condition are involved with apoptosis initiation.
Therefore, flesh quality evaluation based on the alteration of apoptosis process is quite …