Platelet derived bio-products in the form of platelet rich plasma, plasma rich in growth
factors, or plasma-free platelet releasates, are being studied worldwide with the aim of …

Platelet transfusions are often a life-saving intervention, and the use of platelet transfusions
has been increasing. Donor-derived platelet availability can be challenging. Compounding …

Cellular immunotherapy using chimeric antigen receptors (CARs) so far has almost
exclusively used autologous peripheral blood-derived T cells as immune effector cells …

Platelet (PLT) transfusion is indispensable to maintain homeostasis in thrombocytopenic
patients. However, PLT transfusion refractoriness is a common life-threatening condition …

Disparities at the major histocompatibility complex (MHC) antigens and associated minor
antigens trigger harmful immune responses, leading to graft rejection after transplantation …

Platelet demand has increased around the world. However, the inadequacy of donors, the
risk of transfusion-transmitted infections and associated reactions, and the refractory nature …

Abstract Background Semaphorin 7A (Sema7A) is expressed by several different classes of
lymphoid and myeloid cells and is a potent immunomodulator. We examined the role of …

There is a need to store very large numbers of conventional human pluripotent stem cell
(hPSC) lines for their off‐the‐shelf usage in stem cell therapy. Therefore, it is valuable to …

Most adverse blood transfusion (BT) events are immune-mediated and in the majority of
severe reactions antibodies can be identified as causal factors. Alloimmunization not only …

Stem cell technology holds great promise for transfusion medicine, and generation of
platelets from stem cells would be transformative. Platelet transfusions are life saving for …