[HTML][HTML] Fitness, growth and transmissibility of SARS-CoV-2 genetic variants
E Volz - Nature Reviews Genetics, 2023 - nature.com
The massive scale of the global SARS-CoV-2 sequencing effort created new opportunities
and challenges for understanding SARS-CoV-2 evolution. Rapid detection and assessment …
and challenges for understanding SARS-CoV-2 evolution. Rapid detection and assessment …
Transmission dynamics of monkeypox in the United Kingdom: contact tracing study
Objective To analyse the transmission dynamics of the monkeypox outbreak in the UK,
declared a Public Health Emergency of International Concern in July 2022. Design Contact …
declared a Public Health Emergency of International Concern in July 2022. Design Contact …
The rapid replacement of the SARS-CoV-2 Delta variant by Omicron (B. 1.1. 529) in England
The emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B.
1.1. 529 (Omicron) variant caused international concern due to its rapid spread in Southern …
1.1. 529 (Omicron) variant caused international concern due to its rapid spread in Southern …
The P323L substitution in the SARS-CoV-2 polymerase (NSP12) confers a selective advantage during infection
Background The mutational landscape of SARS-CoV-2 varies at the dominant viral genome
sequence and minor genomic variant population. During the COVID-19 pandemic, an early …
sequence and minor genomic variant population. During the COVID-19 pandemic, an early …
[HTML][HTML] City-wide wastewater genomic surveillance through the successive emergence of SARS-CoV-2 Alpha and Delta variants
FS Brunner, MR Brown, I Bassano, H Denise… - Water research, 2022 - Elsevier
Genomic surveillance of SARS-CoV-2 has provided a critical evidence base for public
health decisions throughout the pandemic. Sequencing data from clinical cases has helped …
health decisions throughout the pandemic. Sequencing data from clinical cases has helped …
How do point mutations enhancing the basic character of the RBDs of SARS-CoV-2 variants affect their transmissibility and infectivity capacities?
A Barre, B Klonjkowski, H Benoist, P Rougé - Viruses, 2022 - mdpi.com
The spread of SARS-CoV-2 variants in the population depends on their ability to anchor the
ACE2 receptor in the host cells. Differences in the electrostatic potentials of the spike protein …
ACE2 receptor in the host cells. Differences in the electrostatic potentials of the spike protein …
Replacement dynamics and the pathogenesis of the Alpha, Delta and Omicron variants of SARS-CoV-2
New SARS-CoV-2 variants causing COVID-19 are a major risk to public health worldwide
due to the potential for phenotypic change and increases in pathogenicity, transmissibility …
due to the potential for phenotypic change and increases in pathogenicity, transmissibility …
Nowcasting the 2022 mpox outbreak in England
CE Overton, S Abbott, R Christie… - PLOS Computational …, 2023 - journals.plos.org
In May 2022, a cluster of mpox cases were detected in the UK that could not be traced to
recent travel history from an endemic region. Over the coming months, the outbreak grew …
recent travel history from an endemic region. Over the coming months, the outbreak grew …
The real-time infection hospitalisation and fatality risk across the COVID-19 pandemic in England
T Ward, M Fyles, A Glaser, RS Paton… - Nature …, 2024 - nature.com
The COVID-19 pandemic led to 231,841 deaths and 940,243 hospitalisations in England, by
the end of March 2023. This paper calculates the real-time infection hospitalisation risk (IHR) …
the end of March 2023. This paper calculates the real-time infection hospitalisation risk (IHR) …
Bayesian spatial modelling of localised SARS-CoV-2 transmission through mobility networks across England
In the early phases of growth, resurgent epidemic waves of SARS-CoV-2 incidence have
been characterised by localised outbreaks. Therefore, understanding the geographic …
been characterised by localised outbreaks. Therefore, understanding the geographic …