Therapeutic strategies for sickle cell disease: towards a multi-agent approach
MJ Telen, P Malik, GM Vercellotti - Nature reviews Drug discovery, 2019 - nature.com
For over 100 years, clinicians and scientists have been unravelling the consequences of the
A to T substitution in the β-globin gene that produces haemoglobin S, which leads to the …
A to T substitution in the β-globin gene that produces haemoglobin S, which leads to the …
Modeling and prediction of flow-induced hemolysis: a review
Despite decades of research related to hemolysis, the accuracy of prediction algorithms for
complex flows leaves much to be desired. Fundamental questions remain about how …
complex flows leaves much to be desired. Fundamental questions remain about how …
Quantitative analysis of human red blood cell proteome
AH Bryk, JR Wiśniewski - Journal of proteome research, 2017 - ACS Publications
Red blood cells (RBCs) are the most abundant cell type in the human body. RBCs and, in
particular, their plasma membrane composition have been extensively studied for many …
particular, their plasma membrane composition have been extensively studied for many …
Multiple stiffening effects of nanoscale knobs on human red blood cells infected with Plasmodium falciparum malaria parasite
During its asexual development within the red blood cell (RBC), Plasmodium falciparum (Pf),
the most virulent human malaria parasite, exports proteins that modify the host RBC …
the most virulent human malaria parasite, exports proteins that modify the host RBC …
A coarse-grained red blood cell membrane model to study stomatocyte-discocyte-echinocyte morphologies
An improved red blood cell (RBC) membrane model is developed based on the bilayer
coupling model (BCM) to accurately predict the complete sequence of stomatocyte-discocyte …
coupling model (BCM) to accurately predict the complete sequence of stomatocyte-discocyte …
The nutraceuticals as modern key to achieve erythrocyte oxidative stress fighting in osteoarthritis
A Mariano, I Bigioni, F Misiti, L Fattorini… - Current issues in …, 2022 - mdpi.com
Osteoarthritis (OA), the most common joint disease, shows an increasing prevalence in the
aging population in industrialized countries. OA is characterized by low-grade chronic …
aging population in industrialized countries. OA is characterized by low-grade chronic …
How the spleen reshapes and retains young and old red blood cells: A computational investigation
The spleen, the largest secondary lymphoid organ in humans, not only fulfils a broad range
of immune functions, but also plays an important role in red blood cell's (RBC) life cycle …
of immune functions, but also plays an important role in red blood cell's (RBC) life cycle …
Protective Effect of Bergapten against Human Erythrocyte Hemolysis and Protein Denaturation In Vitro
DB Aidoo, D Konja, IT Henneh… - International Journal of …, 2021 - Wiley Online Library
Bergapten, a furocoumarin found in many medicinal plants, is used for the management of
various conditions. The present in vitro study evaluated the ability of bergapten to prevent …
various conditions. The present in vitro study evaluated the ability of bergapten to prevent …
Model systems for studying lipid oxidation associated with muscle foods: Methods, challenges, and prospects
H Wu, N Tatiyaborworntham… - Critical Reviews in …, 2024 - Taylor & Francis
Lipid oxidation is a complex process in muscle-based foods (red meat, poultry and fish)
causing severe quality deterioration, eg, off-odors, discoloration, texture defects and …
causing severe quality deterioration, eg, off-odors, discoloration, texture defects and …
On the effects of membrane viscosity on transient red blood cell dynamics
Computational Fluid Dynamics (CFD) is currently used to design and improve the hydraulic
properties of biomedical devices, wherein the large scale blood circulation needs to be …
properties of biomedical devices, wherein the large scale blood circulation needs to be …