Single-molecule force spectroscopy has emerged as a powerful tool to investigate the forces
and motions associated with biological molecules and enzymatic activity. The most common …

The possibility for the manipulation of many different samples using only the light from a
laser beam opened the way to a variety of experiments. The technique, known as Optical …

We explain and demonstrate a new method of force and position calibrations for optical
tweezers with back-focal-plane photodetection. The method combines power spectral …

Optical tweezers are widely used to measure molecular forces in biology. Such
measurements are often influenced by a nearby surface that can perturb both the calibration …

Cellular and tissue biosystems emerge from the assembly of their constituent molecules and
obtain a set of specific material properties. To measure these properties and understand …

Optics is usually integrated into robotics as part of intelligent vision systems. At the
microscale, however, optical forces can cause significant acceleration and so optical …

Hypothesis Polyelectrolyte adsorption is considered important in tuning the surface property
and the fate of particles; however, often studied on macroscopic surfaces. To gain insights …

The technically challenging field of single-molecule biophysics has established itself in the
last decade by granting access to detailed information about the fate of individual …

Living cells are composed of active materials, in which forces are generated by the energy
derived from metabolism. Forces and structures self-organize to shape the cell and drive its …

Living cells are active mechanical systems that are able to generate forces. Their structure
and shape are primarily determined by biopolymer filaments and molecular motors that form …