The contextual brain: implications for fear conditioning, extinction and psychopathology

S Maren, KL Phan, I Liberzon - Nature reviews neuroscience, 2013 - nature.com
Contexts surround and imbue meaning to events; they are essential for recollecting the past,
interpreting the present and anticipating the future. Indeed, the brain's capacity to …

The role of emotion regulation in autism spectrum disorder

CA Mazefsky, J Herrington, M Siegel, A Scarpa… - Journal of the American …, 2013 - Elsevier
OBJECTIVE: Autism spectrum disorder (ASD) is associated with amplified emotional
responses and poor emotional control, but little is known about the underlying mechanisms …

How does mindfulness meditation work? Proposing mechanisms of action from a conceptual and neural perspective

BK Hölzel, SW Lazar, T Gard… - Perspectives on …, 2011 - journals.sagepub.com
Cultivation of mindfulness, the nonjudgmental awareness of experiences in the present
moment, produces beneficial effects on well-being and ameliorates psychiatric and stress …

Hippocampal synaptic plasticity, spatial memory and anxiety

DM Bannerman, R Sprengel, DJ Sanderson… - Nature reviews …, 2014 - nature.com
Recent studies using transgenic mice lacking NMDA receptors in the hippocampus
challenge the long-standing hypothesis that hippocampal long-term potentiation-like …

[HTML][HTML] Pathophysiology of depression: do we have any solid evidence of interest to clinicians?

G Hasler - World psychiatry, 2010 - ncbi.nlm.nih.gov
Due to the clinical and etiological heterogeneity of major depressive disorder, it has been
difficult to elucidate its pathophysiology. Current neurobiological theories with the most valid …

Stress reduction correlates with structural changes in the amygdala

BK Hölzel, J Carmody, KC Evans… - Social cognitive and …, 2010 - academic.oup.com
Stress has significant adverse effects on health and is a risk factor for many illnesses.
Neurobiological studies have implicated the amygdala as a brain structure crucial in stress …

[HTML][HTML] Bidirectional control of anxiety-related behaviors in mice: role of inputs arising from the ventral hippocampus to the lateral septum and medial prefrontal cortex

GM Parfitt, R Nguyen, JY Bang, AJ Aqrabawi… - …, 2017 - nature.com
Anxiety is an adaptive response to potentially threatening situations. Exaggerated and
uncontrolled anxiety responses become maladaptive and lead to anxiety disorders. Anxiety …

Neuroimaging of the periaqueductal gray: state of the field

C Linnman, EA Moulton, G Barmettler, L Becerra… - Neuroimage, 2012 - Elsevier
This review and meta-analysis aims at summarizing and integrating the human
neuroimaging studies that report periaqueductal gray (PAG) involvement; 250 original …

Anxiety dissociates dorsal and ventral medial prefrontal cortex functional connectivity with the amygdala at rest

MJ Kim, DG Gee, RA Loucks, FC Davis… - Cerebral …, 2011 - academic.oup.com
Anxiety is linked to compromised interactions between the amygdala and the dorsal and
ventral medial prefrontal cortex (mPFC). While numerous task-based neuroimaging studies …

Bipolar and major depressive disorder: neuroimaging the developmental-degenerative divide

J Savitz, WC Drevets - Neuroscience & Biobehavioral Reviews, 2009 - Elsevier
Both major depressive disorder and bipolar disorder are the subject of a voluminous
imaging and genetics literature. Here, we attempt a comprehensive review of MRI and …