Can the “female protective effect” liability threshold model explain sex differences in autism spectrum disorder?

JD Dougherty, N Marrus, SE Maloney, B Yip, S Sandin… - Neuron, 2022 - cell.com
Male sex is a strong risk factor for autism spectrum disorder (ASD). The leading theory for a"
female protective effect"(FPE) envisions males and females have" differing thresholds" …

The contributions of rare inherited and polygenic risk to ASD in multiplex families

M Cirnigliaro, TS Chang, SA Arteaga… - Proceedings of the …, 2023 - National Acad Sciences
Autism spectrum disorder (ASD) has a complex genetic architecture involving contributions
from both de novo and inherited variation. Few studies have been designed to address the …

Early motor signs in autism spectrum disorder

A Posar, P Visconti - Children, 2022 - mdpi.com
A growing number of literature data suggest the presence of early impairments in the motor
development of children with autism spectrum disorder, which could be often recognized …

Association of intellectual disability with overall and type-specific cardiovascular diseases: a population-based cohort study in Denmark

H Wang, PMY Lee, J Zhang, K Svendsen, F Li, J Li - BMC medicine, 2023 - Springer
Background Individuals with mental health problems have been shown to have an
increased risk of cardiovascular disorder (CVD), but little is known about the risk of early …

Cord blood lipid correlation network profiles are associated with subsequent attention-deficit/hyperactivity disorder and autism spectrum disorder symptoms at 2 years …

K Vacy, S Thomson, A Moore, A Eisner, S Tanner… - …, 2024 - thelancet.com
Background Attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder
(ASD) are neurodevelopmental conditions with early life origins. Alterations in blood lipids …

Heterogeneity and polygenicity in psychiatric disorders: a genome-wide perspective

FR Wendt, GA Pathak, DS Tylee, A Goswami… - Chronic …, 2020 - journals.sagepub.com
Genome-wide association studies (GWAS) have been performed for many psychiatric
disorders and revealed a complex polygenic architecture linking mental and physical health …

Leveraging large genomic datasets to illuminate the pathobiology of autism spectrum disorders

VB Searles Quick, B Wang, MW State - Neuropsychopharmacology, 2021 - nature.com
Abstract “Big data” approaches in the form of large-scale human genomic studies have led
to striking advances in autism spectrum disorder (ASD) genetics. Similar to many other …

Elevated risk of attention deficit hyperactivity disorder (ADHD) in Japanese children with higher genetic susceptibility to ADHD with a birth weight under 2000 g

MS Rahman, N Takahashi, T Iwabuchi, T Nishimura… - BMC medicine, 2021 - Springer
Background Both genetic and pre-and perinatal factors, including birth weight, have been
implicated in the onset of attention deficit hyperactivity disorder (ADHD) traits among …

[PDF][PDF] Autismo no Brasil: uma revisão sobre estudos em neurogenética

VGO Evangelho, FMR Costa, HC Castro… - Revista …, 2021 - researchgate.net
Objetivo. Identificar artigos, dissertações e teses brasileiras relacionadas a neurogenética
do autismo, entre os anos de 2017 e 2020. Método. A triagem dos trabalhos publicados nas …

[HTML][HTML] The association between screen time and genetic risks for neurodevelopmental disorders in children

N Takahashi, KJ Tsuchiya, A Okumura, T Harada… - Psychiatry …, 2023 - Elsevier
Whether longer screen time in infancy increases risk of neurodevelopmental disorders
(NDDs) such as autism spectrum disorder (ASD) and ADHD has long been debated, but no …