The unique chemistry of small, strained carbocyclic systems has long captivated organic
chemists from a theoretical and fundamental standpoint. A resurgence of interest in strained …

Tetronic acid, a versatile synthon, has been extensively investigated by numerous
researchers in synthetic chemistry due to its crucial role in synthesizing heterocycles which …

The replacement of aryl rings with saturated carbocyclic structures has garnered significant
interest in drug discovery due to the potential for improved pharmacokinetic properties upon …

Sulfonyl fluorides have attracted considerable and growing research interests from various
disciplines, which raises a high demand for novel and effective methods to access this class …

Identification of rigid counterparts for common flexible scaffolds is crucial to the
advancement of medicinal chemistry. Here we showcase a new class of building blocks, 2, 5 …

An electron donor–acceptor (EDA) complex photoactivation strategy for radical
fluorosulfonylation is disclosed for the first time. Simply upon blue light irradiation, the FSO2 …

We report a transition-metal-free deborylative cyclization approach to synthesize
enantioenriched secondary and tertiary cyclopropylboronates using γ-phosphate-containing …

A nickel-catalyzed reductive cross-coupling of cyclopropylamine NHP esters with (hetero)
aryl halides is reported. This efficient protocol provides direct access to 1 …

A novel cascade approach is presented for the synthesis of FSO2-functionalized
tetrahydropyridines from propargyl alcohols, FSO2Cl, and anilines. This strategy …

A radical hydro-fluorosulfonylation of propargyl alcohols with FSO2Cl is presented based on
the photoactivation of the electron donor–acceptor (EDA) complex. The reaction avoids the …