Three-dimensional (3D) printing plays an important role in cardiovascular disease through
the use of personalised models that replicate the normal anatomy and its pathology with …

The adult human heart cannot regain complete cardiac function following tissue injury,
making cardiac regeneration a current clinical unmet need. There are a number of clinical …

Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia treatable with
antiarrhythmic drugs; however, patient responses remain highly variable. Human induced …

Cardiac tissue engineering (CTE) is a promising way for the restoration of injured cardiac
tissue in the healthcare system. The development of biodegradable scaffolds with …

Experimental studies and clinical trials of nanoparticles for treating diseases are increasing
continuously. However, the reach to the market does not correlate with these efforts due to …

There is critical need for a predictive model of human cardiac physiology in drug
development to assess compound effects on human tissues. In vitro two-dimensional …

Introduction: Skeletal muscle is a major contributor to whole-body energy homeostasis and
the utilization of fatty acids and glucose. At present, 2D cell models have been the most used …

Evaluation of arrhythmogenic drugs is required by regulatory agencies before any new
compound can obtain market approval. Despite rigorous review, cardiac disorders remain …

Since cardiovascular diseases (CVDs) are globally one of the leading causes of death, of
which myocardial infarction (MI) can cause irreversible damage and decrease survivors' …

The use of human cardiac organoids (hCOs) as 3D in vitro models for cardiovascular
research has shown great promise. Human pluripotent stem cells (hPSCs) have proven to …