Nanoparticles have demonstrated significant advancements in potential oral delivery of
insulin. In this publication, we review the current status of polymeric, inorganic and solid-lipid …

SIXTEEN million individuals in the United States with type 2 diabetes mellitus and an
additional 30–40 million with impaired glucose tolerance result in health care costs …

Since its discovery and isolation, exogenous insulin has dramatically changed the outlook
for patients with diabetes. However, even when patients strictly follow an insulin regimen …

The advent of insulin almost 80 years ago revolutionised treatment of diabetes and must be
one of the most outstanding achievements of twentieth century medicine. Since then, there …

The primary goal of treatment of Type I (insulin-dependent) diabetes mellitus, both at onset
and after several years duration, is maintenance of near-normoglycaemia [1] to prevent the …

PURPOSE: To compare the efficacy and safety of subcutaneous insulin lispro with that of a
standard low-dose intravenous infusion protocol of regular insulin in patients with …

OBJECTIVE—In this prospective, randomized, open trial, we compared the efficacy and
safety of aspart insulin given subcutaneously at different time intervals to a standard low …

The secondary occurrence of type 2 diabetes with various hormonal diseases (eg pituitary,
adrenal and/or thyroid diseases) is a recurrent observation. Indeed, impaired glucose …

The aim of insulin replacement therapy is to normalize blood glucose in order to reduce the
complications of diabetes. The pharmacokinetics of the traditional insulin preparations …

OBJECTIVE: To compare long-term glycemic control and safety of using insulin aspart (IAsp)
with that of regular human insulin (HI). RESEARCH DESIGN AND METHODS: This was a …