Patients are exposed to numerous prescribed and over-the-counter medications.
Unfortunately, drugs remain a relatively common cause of acute and chronic kidney injury. A …

The management of pain in patients with chronic kidney disease (CKD) is challenging for
many reasons. These patients have increased susceptibility to adverse drug effects due to …

Gouty arthritis is a very familiar inflammatory arthritis. Controlling inflammation is the key to
preventing gouty arthritis. However, colchicine, the most highly represented drug used in …

The term cardiorenal syndrome (CRS) increasingly has been used without a consistent or
well-accepted definition. To include the vast array of interrelated derangements, and to …

Doxorubicin (DOX)-induced toxicity and resistance are major obstacles in chemotherapeutic
approaches. Despite effective in the treatment of numerous malignancies, some clinicians …

Drug-induced kidney disease occurs primarily in patients with underlying risk factors. A
number of factors enhance the vulnerability of the kidney to the nephrotoxic effects of drugs …

Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit the isoenzymes COX-1 and COX-2 of
cyclooxygenase (COX). Renal side effects (eg, kidney function, fluid and urinary electrolyte …

between the number of iodine atoms and the number of dissolved particles. The higher the
ratio, the better is the attenuation of x-rays because there are more iodine atoms for fewer …

Background: Most epidemiological studies evaluating the association between nonsteroidal
anti-inflammatory drugs (NSAIDs) and acute renal failure (ARF) found an increased risk for …

The main mechanisms of nephrotoxicity are vasoconstriction, altered intraglomerular
hemodynamics, tubular cell toxicity, interstitial nephritis, crystal deposition, thrombotic …