Understanding the role of the perivascular space in cerebral small vessel disease

R Brown, H Benveniste, SE Black… - Cardiovascular …, 2018 - academic.oup.com
Small vessel diseases (SVDs) are a group of disorders that result from pathological
alteration of the small blood vessels in the brain, including the small arteries, capillaries and …

Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges

L Pantoni - The Lancet Neurology, 2010 - thelancet.com
The term cerebral small vessel disease refers to a group of pathological processes with
various aetiologies that affect the small arteries, arterioles, venules, and capillaries of the …

[HTML][HTML] Glymphatic clearance function in patients with cerebral small vessel disease

W Zhang, Y Zhou, J Wang, X Gong, Z Chen, X Zhang… - Neuroimage, 2021 - Elsevier
Few studies have focused on the connection between glymphatic dysfunction and cerebral
small vessel disease (CSVD), partially due to the lack of non-invasive methods to measure …

Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration

JM Wardlaw, EE Smith, GJ Biessels… - The Lancet …, 2013 - thelancet.com
Cerebral small vessel disease (SVD) is a common accompaniment of ageing. Features seen
on neuroimaging include recent small subcortical infarcts, lacunes, white matter …

[HTML][HTML] Cerebral perivascular spaces visible on magnetic resonance imaging: development of a qualitative rating scale and its observer reliability

GM Potter, FM Chappell, Z Morris… - Cerebrovascular …, 2015 - karger.com
Background: Perivascular spaces (PVS) are an important component of cerebral small
vessel disease (SVD), several inflammatory disorders, hypertension and blood-brain barrier …

MRI-visible perivascular spaces in cerebral amyloid angiopathy and hypertensive arteriopathy

A Charidimou, G Boulouis, M Pasi, E Auriel… - Neurology, 2017 - AAN Enterprises
Objective: To assess MRI-visible enlarged perivascular spaces (EPVS) burden and different
topographical patterns (in the centrum semiovale [CSO] and basal ganglia [BG]) in 2 …

Enlarged perivascular spaces on MRI are a feature of cerebral small vessel disease

FN Doubal, AMJ MacLullich, KJ Ferguson, MS Dennis… - Stroke, 2010 - Am Heart Assoc
Background and Purpose—Enlarged perivascular spaces in the brain are common but
generally overlooked and of uncertain pathophysiology. They may reflect underlying …

Perivascular spaces and their associations with risk factors, clinical disorders and neuroimaging features: a systematic review and meta-analysis

F Francis, L Ballerini… - International Journal of …, 2019 - journals.sagepub.com
Background Perivascular spaces, visible on brain magnetic resonance imaging, are thought
to be associated with small vessel disease, neuroinflammation, and to be important for …

Enlarged perivascular spaces and cerebral small vessel disease

GM Potter, FN Doubal, CA Jackson… - … journal of stroke, 2015 - journals.sagepub.com
Background and aims Enlarged perivascular spaces (also known as Virchow-Robin spaces)
on T2-weighted brain magnetic resonance imaging are common, but their etiology, and …

Severity of dilated Virchow-Robin spaces is associated with age, blood pressure, and MRI markers of small vessel disease: a population-based study

YC Zhu, C Tzourio, A Soumaré, B Mazoyer, C Dufouil… - Stroke, 2010 - Am Heart Assoc
Background and Purpose—Little is known about the risk factors of dilated Virchow-Robin
spaces (dVRS) and their relation with other markers of brain small vessel disease. We …