The mechanisms that control the sizes of a body and its many parts remain among the great
puzzles in developmental biology. Why do animals grow to a species‐specific body size …

Highlights•bHLH-PAS proteins Met and Tai form a JH receptor that mediates JH function in
vivo.•The Met–Tai receptor complex is a JH-activated transcription factor.•JH activates Met …

Populations of pollinators are in decline worldwide. These declines are best documented in
honey bees and are due to a combination of stressors. In particular, pesticides have been …

Juvenile hormones (JHs) play a major role in controlling development and reproduction in
insects and other arthropods. Synthetic JH-mimicking compounds such as methoprene are …

Our understanding of JH biosynthesis has significantly changed in the last years. In this
review I would like to discuss the following topics:(1) the progresses in understanding the JH …

Sex-determination systems can be divided into two groups: genotypic sex determination
(GSD) and environmental sex determination (ESD). ESD is an adaptive life-history strategy …

Corpus allatum (CA) ablation results in juvenile hormone (JH) deficiency and pupal lethality
in Drosophila. The fly CA produces and releases three sesquiterpenoid hormones: JH III …

Arthropods have long been utilized as models to explore molecular function, and the
findings derived from them can be applied throughout metazoa, including as a basis for …

RNA interference (RNAi) is a powerful approach for elucidating gene functions in a variety of
organisms, including mosquitoes and many other insects. Little has been done, however, to …

Nuclear receptors (NRs) fulfill key roles in the coordination of postembryonal developmental
transitions in animal species. They control the metamorphosis and sexual maturation in …