Ultrasensitive and highly specific lateral flow assays for point-of-care diagnosis

Y Liu, L Zhan, Z Qin, J Sackrison, JC Bischof - ACS nano, 2021 - ACS Publications
Lateral flow assays (LFAs) are paper-based point-of-care (POC) diagnostic tools that are
widely used because of their low cost, ease of use, and rapid format. Unfortunately …

Blood-based cancer biomarkers in liquid biopsy: a promising non-invasive alternative to tissue biopsy

J Marrugo-Ramírez, M Mir, J Samitier - International journal of molecular …, 2018 - mdpi.com
Cancer is one of the greatest threats facing our society, being the second leading cause of
death globally. Currents strategies for cancer diagnosis consist of the extraction of a solid …

Extracellular vesicle quantification and characterization: common methods and emerging approaches

TA Hartjes, S Mytnyk, GW Jenster, V van Steijn… - Bioengineering, 2019 - mdpi.com
Extracellular vesicles (EVs) are a family of small membrane vesicles that carry information
about cells by which they are secreted. Growing interest in the role of EVs in intercellular …

A sensitive aptasensor based on a hemin/G‐Quadruplex‐assisted signal amplification strategy for electrochemical detection of gastric cancer exosomes

R Huang, L He, Y Xia, H Xu, C Liu, H Xie, S Wang… - Small, 2019 - Wiley Online Library
Emerging evidence indicates that exosomes derived from gastric cancer cells enhance
tumor migration and invasion through the modulation of the tumor microenvironment …

Single-exosome-counting immunoassays for cancer diagnostics

C Liu, X Xu, B Li, B Situ, W Pan, Y Hu, T An, S Yao… - Nano …, 2018 - ACS Publications
Exosomes shed by tumor cells have been recognized as promising biomarkers for cancer
diagnostics due to their unique composition and functions. Quantification of low …

Lateral flow assays towards point-of-care cancer detection: A review of current progress and future trends

T Mahmoudi, M de la Guardia, B Baradaran - TrAC Trends in Analytical …, 2020 - Elsevier
Cancer is one of the main causes of mortality and morbidity worldwide. However, its early
non-invasive detection via quantification of appropriate biomarkers can significantly reduce …

Integrated microfluidic-SERS for exosome biomarker profiling and osteosarcoma diagnosis

Z Han, X Peng, Y Yang, J Yi, D Zhao, Q Bao… - Biosensors and …, 2022 - Elsevier
Osteosarcoma is one of the most frequent primary sarcoma of bone among adolescents.
Early diagnosis of osteosarcoma is the key factor to achieve high survival rate of patients …

Screening and multiple detection of cancer exosomes using an SERS-based method

Z Wang, S Zong, Y Wang, N Li, L Li, J Lu, Z Wang… - Nanoscale, 2018 - pubs.rsc.org
As a kind of most important cancer biomarker, exosomes are getting more frequently
investigated in cancer diagnosis. In this study, we proposed an SERS-based method for the …

[HTML][HTML] Small extracellular vesicles in cancer

K Abhange, A Makler, Y Wen, N Ramnauth, W Mao… - Bioactive Materials, 2021 - Elsevier
Extracellular vesicles (EV) are lipid-bilayer enclosed vesicles in submicron size that are
released from cells. A variety of molecules, including proteins, DNA fragments, RNAs, lipids …

Analysis and biomedical applications of functional cargo in extracellular vesicles

F Qian, Z Huang, H Zhong, Q Lei, Y Ai, Z Xie, T Zhang… - ACS …, 2022 - ACS Publications
Extracellular vesicles (EVs) can facilitate essential communication among cells in a range of
pathophysiological conditions including cancer metastasis and progression, immune …