The heat shock proteins (HSPs) are ubiquitous and conserved protein families in both
prokaryotic and eukaryotic organisms, and they maintain cellular proteostasis and protect …

Each protein must be synthesized with the correct amino acid sequence, folded into its
native structure, and transported to a relevant subcellular location and protein complex. If …

Although oxidants clearly possess the capacity to behave in a random and destructive
fashion, growing evidence suggests that in many instances the production of reactive …

An elevated temperature has many aetiologies, both infective and non-infective, and while
the fever of sepsis probably confers benefit, there is increasing evidence that the central …

Spinal cord injury (SCI) is a neurological disorder associated with the loss of sensory and
motor function. Understanding the precise dysregulated signaling pathways, especially …

The role of energy in ecological processes has hitherto been considered primarily from the
standpoint that energy supply is limited. That is, traditional resource‐based ecological and …

Ischemic tolerance describes the adaptive biological response of cells and organs that is
initiated by preconditioning (ie, exposure to stressor of mild severity) and the associated …

The heat shock response (HSR) is a highly conserved cellular pathway that is responsible
for stress relief and the refolding of denatured proteins [1]. When a host cell is exposed to …

Spontaneous and sensory-evoked activity propagates across varying spatial scales in the
mammalian cortex, but technical challenges have limited conceptual links between the …

In Alzheimer's disease (AD), Parkinson's disease (PD), dementia with Lewy bodies (DLB)
and amyotrophic lateral sclerosis (ALS), neuroinflammatory responses are considered to …