Single-cell RNA-seq: advances and future challenges

AE Saliba, AJ Westermann, SA Gorski… - Nucleic acids …, 2014 - academic.oup.com
Phenotypically identical cells can dramatically vary with respect to behavior during their
lifespan and this variation is reflected in their molecular composition such as the …

Nanopores in graphene and other 2D materials: a decade's journey toward sequencing

H Qiu, W Zhou, W Guo - ACS nano, 2021 - ACS Publications
Nanopore techniques offer a low-cost, label-free, and high-throughput platform that could be
used in single-molecule biosensing and in particular DNA sequencing. Since 2010 …

The Oxford Nanopore MinION: delivery of nanopore sequencing to the genomics community

M Jain, HE Olsen, B Paten, M Akeson - Genome biology, 2016 - Springer
Nanopore DNA strand sequencing has emerged as a competitive, portable technology.
Reads exceeding 150 kilobases have been achieved, as have in-field detection and …

The evolution of nanopore sequencing

Y Wang, Q Yang, Z Wang - Frontiers in genetics, 2015 - frontiersin.org
The “1000Genome”projecthasbeendrawingincreasingattention….Nanoporesequencing,
thethird-generation,isbelievedtobeoneofthemostpromisingsequ…“ 1000 Genome” while the …

Advances in the profiling of N6-methyladenosine (m6A) modifications

H Zheng, X Zhang, N Sui - Biotechnology Advances, 2020 - Elsevier
Over 160 RNA modifications have been identified, including N 7-methylguanine (m 7 G), N 6-
methyladenosine (m 6 A), and 5-methylcytosine (m 5 C). These modifications play key roles …

Overview of high throughput sequencing technologies to elucidate molecular pathways in cardiovascular diseases

JM Churko, GL Mantalas, MP Snyder, JC Wu - Circulation research, 2013 - Am Heart Assoc
High throughput sequencing technologies have become essential in studies on genomics,
epigenomics, and transcriptomics. Although sequencing information has traditionally been …

Nanoscale electrochemistry revisited

SM Oja, Y Fan, CM Armstrong, P Defnet… - Analytical …, 2016 - ACS Publications
The field of nanoscale electrochemistry has received enormous attention in the last several
years with numerous exciting advancements reported in several rapidly growing areas …

Fabricating nanopores with diameters of sub-1 nm to 3 nm using multilevel pulse-voltage injection

I Yanagi, R Akahori, T Hatano, K Takeda - Scientific reports, 2014 - nature.com
To date, solid-state nanopores have been fabricated primarily through a focused-electronic
beam via TEM. For mass production, however, a TEM beam is not suitable and an …

New insights for biosensing: Lessons from microbial defense systems

Y Wan, C Zong, X Li, A Wang, Y Li, T Yang… - Chemical …, 2022 - ACS Publications
Microorganisms have gained defense systems during the lengthy process of evolution over
millions of years. Such defense systems can protect them from being attacked by invading …

Biological nanopores: Engineering on demand

A Crnković, M Srnko, G Anderluh - Life, 2021 - mdpi.com
Nanopore-based sensing is a powerful technique for the detection of diverse organic and
inorganic molecules, long-read sequencing of nucleic acids, and single-molecule analyses …