In this review, we detail the changes and the relevant features that are applied to
neuroendocrine neoplasms (NENs) in the 2022 WHO Classification of Endocrine and …

Abstract The 2021 WHO Classification of Thoracic Tumours was published earlier this year,
with classification of lung tumors being one of the chapters. The principles remain those of …

This review summarizes key recent developments relevant to the pathologic diagnosis of
lung neuroendocrine neoplasms, including carcinoids, small cell lung carcinoma (SCLC) …

Lung cancer causes the largest number of cancer-related deaths in the world. Most (85%) of
lung cancers are classified as non-small-cell lung cancer (NSCLC) and small-cell lung …

Carcinoids and large cell neuroendocrine carcinomas (LCNECs) are rare neuroendocrine
lung tumors. Here we provide an overview of the most updated data on the molecular …

Purpose: The optimal systemic treatment for pulmonary large-cell neuroendocrine
carcinoma (LCNEC) is still under debate. Previous studies showed that LCNEC with …

Large cell neuroendocrine carcinoma (LCNECs) and small cell lung carcinomas (SCLCs)
are high-grade neuroendocrine carcinomas of the lung with very aggressive behavior and …

High-grade neuroendocrine neoplasms (HG-NENs) are clinically aggressive diseases, the
classification of which has recently been redefined. They now include both poorly …

Histopathological classifications of neuroendocrine neoplasms (NEN) change regularly and
the latest WHO classification published in 2022, which concerns all NEN in the body …

Large cell neuroendocrine carcinoma of the lung (LCNEC) is a rare and highly aggressive
type of lung cancer, with a complex biology that shares similarities with both small-cell lung …