Immunomodulatory biomaterials for tissue repair

R Whitaker, B Hernaez-Estrada… - Chemical …, 2021 - ACS Publications
All implanted biomaterials are targets of the host's immune system. While the host
inflammatory response was once considered a detrimental force to be blunted or avoided, in …

Design, printing, and engineering of regenerative biomaterials for personalized bone healthcare

Z Jia, X Xu, D Zhu, Y Zheng - Progress in Materials Science, 2023 - Elsevier
Trauma-and disease-related skeletal defects and illnesses are plaguing millions of people
especially in an ageing globe. Recently, the convergence of additive manufacturing (AM) …

Advanced biomaterials for regulating polarization of macrophages in wound healing

J Mao, L Chen, Z Cai, S Qian, Z Liu… - Advanced Functional …, 2022 - Wiley Online Library
Macrophage immunotherapy is an emerging treatment strategy that modulates the immune
system to promote wound healing. The functionality and regeneration of tissue depend on …

Immunopolarization-regulated 3D printed-electrospun fibrous scaffolds for bone regeneration

X Liu, M Chen, J Luo, H Zhao, X Zhou, Q Gu, H Yang… - Biomaterials, 2021 - Elsevier
Abstract Three-dimension (3D)-printed bioscaffolds are precise and personalized for bone
regeneration. However, customized 3D scaffolds may activate the immune response in vivo …

Immunomodulatory strategies for bone regeneration: a review from the perspective of disease types

N Su, C Villicana, F Yang - Biomaterials, 2022 - Elsevier
Tissue engineering strategies for treating bone loss to date have largely focused on
targeting stem cells or vascularization. Immune cells, including macrophages and T cells …

Mild photothermal‐stimulation based on injectable and photocurable hydrogels orchestrates immunomodulation and osteogenesis for high‐performance bone …

M Wu, H Liu, Y Zhu, F Chen, Z Chen, L Guo, P Wu, G Li… - Small, 2023 - Wiley Online Library
A photoactivated bone scaffold integrated with minimally invasive implantation and mild
thermal‐stimulation capability shows great promise in the repair and regeneration of …

Mesenchymal stromal exosome–functionalized scaffolds induce innate and adaptive immunomodulatory responses toward tissue repair

N Su, Y Hao, F Wang, W Hou, H Chen, Y Luo - Science advances, 2021 - science.org
Designing scaffolds capable of inducing and guiding appropriate immune responses holds
promise for tissue repair/regeneration. Biofunctional scaffolds were here prepared by …

Advanced strategies of biomimetic tissue‐engineered grafts for bone regeneration

C Xie, J Ye, R Liang, X Yao, X Wu… - Advanced …, 2021 - Wiley Online Library
The failure to repair critical‐sized bone defects often leads to incomplete regeneration or
fracture non‐union. Tissue‐engineered grafts have been recognized as an alternative …

Bioinspired piezoelectric periosteum to augment bone regeneration via synergistic immunomodulation and osteogenesis

H Liu, Y Shi, Y Zhu, P Wu, Z Deng, Q Dong… - … Applied Materials & …, 2023 - ACS Publications
Ideal periosteum materials are required to participate in a sequence of bone repair-related
physiological events, including the initial immune response, endogenous stem cell …

Electrospun nanofibrous materials for wound healing

Y Dong, Y Zheng, K Zhang, Y Yao, L Wang, X Li… - Advanced Fiber …, 2020 - Springer
Wound dressing materials which are capable of meeting the demands of accelerating
wound closure and promoting wound healing process have being highly desired …