Meningeal lymphatics clear erythrocytes that arise from subarachnoid hemorrhage
J Chen, L Wang, H Xu, L Xing, Z Zhuang… - Nature …, 2020 - nature.com
Extravasated erythrocytes in cerebrospinal fluid (CSF) critically contribute to the
pathogenesis of subarachnoid hemorrhage (SAH). Meningeal lymphatics have been …
pathogenesis of subarachnoid hemorrhage (SAH). Meningeal lymphatics have been …
Blood and lymphatic vasculatures on-chip platforms and their applications for organ-specific in vitro modeling
The human circulatory system is divided into two complementary and different systems, the
cardiovascular and the lymphatic system. The cardiovascular system is mainly concerned …
cardiovascular and the lymphatic system. The cardiovascular system is mainly concerned …
[HTML][HTML] Implications of lymphatic alterations in the pathogenesis and treatment of inflammatory bowel disease
L Zhang, DKW Ocansey, L Liu, CV Olovo… - Biomedicine & …, 2021 - Elsevier
Inflammatory bowel disease (IBD) is characterized by intense immune dysregulation, gut
microbiota imbalance, and intestinal epithelium destruction. Among the factors that …
microbiota imbalance, and intestinal epithelium destruction. Among the factors that …
Lymphangiocrine signals are required for proper intestinal repair after cytotoxic injury
The intestinal epithelium undergoes continuous renewal and has an exceptional capacity to
regenerate after injury. Maintenance and proliferation of intestinal stem cells (ISCs) are …
regenerate after injury. Maintenance and proliferation of intestinal stem cells (ISCs) are …
Lipopolysaccharides modulate intestinal epithelial permeability and inflammation in a species-specific manner
M Stephens, PY von der Weid - Gut microbes, 2020 - Taylor & Francis
Patients presenting with Inflammatory bowel disease have been shown to exhibit an altered
microbiome in both Crohn's disease and Ulcerative colitis. This shift in the microbial content …
microbiome in both Crohn's disease and Ulcerative colitis. This shift in the microbial content …
Exosomes derived from human umbilical cord mesenchymal stem cells regulate lymphangiogenesis via the miR-302d-3p/VEGFR3/AKT axis to ameliorate …
L Zhang, J Yuan, DKW Ocansey, B Lu, A Wan… - International …, 2022 - Elsevier
Background Exosomes released from human umbilical cord mesenchymal stem cell
(hucMSC-Ex) have been revealed to hold great potential for the development of new …
(hucMSC-Ex) have been revealed to hold great potential for the development of new …
[HTML][HTML] IL-17-driven induction of Paneth cell antimicrobial functions protects the host from microbiota dysbiosis and inflammation in the ileum
T Brabec, M Vobořil, D Schierová, E Valter… - Mucosal …, 2023 - Elsevier
Interleukin (IL)-17 protects epithelial barriers by inducing the secretion of antimicrobial
peptides. However, the effect of IL-17 on Paneth cells (PCs), the major producers of …
peptides. However, the effect of IL-17 on Paneth cells (PCs), the major producers of …
The role of the lymphatic system in the pathogenesis and treatment of inflammatory bowel disease
D Nikolakis, FAE de Voogd, MJ Pruijt… - International journal of …, 2022 - mdpi.com
Although the number of therapeutic options for the treatment of inflammatory bowel disease
(IBD) has increased in recent years, patients suffer from decreased quality of life due to non …
(IBD) has increased in recent years, patients suffer from decreased quality of life due to non …
Polysaccharide from Smilax glabra Roxb Mitigates Intestinal Mucosal Damage by Therapeutically Restoring the Interactions between Gut Microbiota and Innate …
M Abaidullah, S La, M Liu, B Liu, Y Cui, Z Wang, H Sun… - Nutrients, 2023 - mdpi.com
Smilax glabra Roxb (S. glabra) is a conventional Chinese medicine that is mainly used for
the reliability of inflammation. However, bioactive polysaccharides from S. glabra (SGPs) …
the reliability of inflammation. However, bioactive polysaccharides from S. glabra (SGPs) …
Immunomodulatory properties of the lymphatic endothelium in the tumor microenvironment
C Viúdez-Pareja, E Kreft… - Frontiers in …, 2023 - frontiersin.org
The tumor microenvironment (TME) is an intricate complex and dynamic structure composed
of various cell types, including tumor, stromal and immune cells. Within this complex …
of various cell types, including tumor, stromal and immune cells. Within this complex …