Transforming growth factor beta (TGF‐β) isoforms in wound healing and fibrosis

MK Lichtman, M Otero‐Vinas… - Wound Repair and …, 2016 - Wiley Online Library
Scar formation, with persistent alteration of the normal tissue structure, is an undesirable and
significant result of both wound healing and fibrosing disorders. There are few strategies to …

Keloids: a review of therapeutic management

SF Ekstein, SP Wyles, SL Moran… - International journal of …, 2021 - Wiley Online Library
Keloid scar formation arises from a disorganized fibroproliferative collagen response that
extends beyond the original wound margins because of excessive production of …

Current and upcoming therapies to modulate skin scarring and fibrosis

JQ Coentro, E Pugliese, G Hanley, M Raghunath… - Advanced drug delivery …, 2019 - Elsevier
Skin is the largest organ of the human body. Being the interface between the body and the
outer environment, makes it susceptible to physical injury. To maintain life, nature has …

Scar management in burn injuries using drug delivery and molecular signaling: current treatments and future directions

S Amini-Nik, Y Yousuf, MG Jeschke - Advanced drug delivery reviews, 2018 - Elsevier
In recent decades, there have been tremendous improvements in burn care that have
allowed patients to survive severe burn injuries that were once fatal. However, a major …

Fibrosis in burns: an overview of mechanisms and therapies

S Faour, M Farahat, A Aijaz… - American Journal of …, 2023 - journals.physiology.org
Scar development remains a common occurrence and a major healthcare challenge
affecting the lives of millions of patients annually. Severe injuries to the skin, such as burns …

Invasive fibrous thyroiditis (Riedel thyroiditis): the Mayo Clinic experience, 1976–2008

MM Fatourechi, ID Hay, B McIver, TJ Sebo… - Thyroid, 2011 - liebertpub.com
Background: Invasive fibrous thyroiditis (IFT) is the rarest form of thyroiditis, and reports are
often limited to case reports and small case series. In this study, we aimed to summarize our …

Scarless wound healing: from development to senescence

H Pratsinis, E Mavrogonatou, D Kletsas - Advanced drug delivery reviews, 2019 - Elsevier
An essential element of tissue homeostasis is the response to injuries, cutaneous wound
healing being the most studied example. In the adults, wound healing aims at quickly …

[HTML][HTML] Innovative therapies in the treatment of keloids and hypertrophic scars

MH Viera, S Amini, W Valins… - The Journal of clinical and …, 2010 - ncbi.nlm.nih.gov
Keloids and hypertrophic scars are benign fibrous overgrowths of scar tissue, which results
from an abnormal response to trauma. Several therapeutic modalities have been described …

The role of estrogen deficiency in skin ageing and wound healing

E Emmerson, MJ Hardman - Biogerontology, 2012 - Springer
The links between hormonal signalling and lifespan have been well documented in a range
of model organisms. For example, in C. elegans or D. melanogaster, lifespan can be …

Treatment of keloids and hypertrophic scars. Position statement of the Brazilian expert group GREMCIQ

GV Oliveira, LD Metsavaht, BV Kadunc… - Journal of the …, 2021 - Wiley Online Library
Keloids (K) and hypertrophic scars (HS) are abnormal responses to wound healing that
occur as the result of dermal inflammation. Despite the advances on their treatment, many …