The role of Nrf2 in the antioxidant cellular response to medical ozone exposure

M Galiè, V Covi, G Tabaracci, M Malatesta - International Journal of …, 2019 - mdpi.com
Ozone (O3) is a natural, highly unstable atmospheric gas that rapidly decomposes to
oxygen. Although not being a radical molecule, O3 is a very strong oxidant and therefore it is …

[HTML][HTML] Ozone: a natural bioactive molecule with antioxidant property as potential new strategy in aging and in neurodegenerative disorders

C Scassellati, AC Galoforo, C Bonvicini… - Ageing Research …, 2020 - Elsevier
Abstract Systems medicine is founded on a mechanism-based approach and identifies in
this way specific therapeutic targets. This approach has been applied for the transcription …

Grape seed procyanidin extract protects against Pb-induced lung toxicity by activating the AMPK/Nrf2/p62 signaling axis

J Lu, H Jiang, B Liu, R Baiyun, S Li, Y Lv, D Li… - Food and Chemical …, 2018 - Elsevier
Lead (Pb) is one of the most relevant heavy metals contaminants which cause oxidative
stress and threaten human health. The lung is one of the organs most severely damaged by …

Randomized controlled clinical trial on bleaching sensitivity and whitening efficacy of hydrogen peroxide versus combinations of hydrogen peroxide and ozone

MK Al-Omiri, AA Al Nazeh, AM Kielbassa, E Lynch - Scientific reports, 2018 - nature.com
The clinical efficacy regarding bleaching sensitivity and tooth shade lightening using a
standard hydrogen peroxide (H2O2) bleaching gel was compared with the additional use of …

Lactobacillus plantarum LP33 attenuates Pb-induced hepatic injury in rats by reducing oxidative stress and inflammation and promoting Pb excretion

T Hu, J Song, W Zeng, J Li, H Wang, Y Zhang… - Food and Chemical …, 2020 - Elsevier
Lead (Pb) is one of the most common heavy metals and is harmful to human health. The
liver is considered as a major target organ for Pb poisoning. Although probiotics have been …

Ozone protects the rat lung from ischemia-reperfusion injury by attenuating NLRP3-mediated inflammation, enhancing Nrf2 antioxidant activity and inhibiting …

Z Wang, A Zhang, W Meng, T Wang, D Li, Z Liu… - European Journal of …, 2018 - Elsevier
Ischemia-reperfusion injury (IRI) is a major cause of lung dysfunction during cardiovascular
surgery, heart transplantation and cardiopulmonary bypass procedures, and the …

Ozone therapy: a potential therapeutic adjunct for improving female reproductive health

Z Merhi, B Garg, R Moseley-LaRue… - Medical gas …, 2019 - journals.lww.com
Ozone is emerging as a new adjunct therapeutic agent for female infertility. We here present
a review of the literature, to date, pertaining to the effect of ozone therapy on tubal, ovarian …

Treatment of symptomatic, deep, almost cariously exposed lesions using ozone

MK Al-Omiri, NM Alqahtani, NM Alahmari… - Scientific Reports, 2021 - nature.com
The aim of this controlled randomized crossover study was to assess post-treatment pain
and the need for root canal treatment after the use of a traditional caries removal method …

Inflammatory and oxidative stress responses of healthy adults to changes in personal air pollutant exposure

X Hu, L He, J Zhang, X Qiu, Y Zhang, J Mo… - Environmental …, 2020 - Elsevier
Exposure to air pollutants has been associated with respiratory and cardiovascular mortality,
but the underlying molecular mechanisms remain inadequately understood. We aimed to …

An adaptive drug-releasing contact lens for personalized treatment of ocular infections and injuries

R Sun, J Zhang, X Chen, Y Deng, J Gou, T Yin… - Journal of Controlled …, 2024 - Elsevier
This research introduces an innovative solution to address the challenges of bacterial
keratitis and alkali burns. Current treatments for bacterial keratitis and alkali burns rely on …