Management of drug-resistant tuberculosis
Drug-resistant tuberculosis is a major public health concern in many countries. Over the past
decade, the number of patients infected with Mycobacterium tuberculosis resistant to the …
decade, the number of patients infected with Mycobacterium tuberculosis resistant to the …
Point-of-care diagnostic tests for tuberculosis disease
Rapid diagnosis is one key pillar to end tuberculosis (TB). Point-of-care tests (POCTs)
facilitate early detection, immediate treatment, and reduced transmission of TB disease. This …
facilitate early detection, immediate treatment, and reduced transmission of TB disease. This …
The changing paradigm of drug-resistant tuberculosis treatment: successes, pitfalls, and future perspectives
N Dookie, SL Ngema, R Perumal… - Clinical Microbiology …, 2022 - Am Soc Microbiol
Drug-resistant tuberculosis (DR-TB) remains a global crisis due to the increasing incidence
of drug-resistant forms of the disease, gaps in detection and prevention, models of care, and …
of drug-resistant forms of the disease, gaps in detection and prevention, models of care, and …
Impact and cost-effectiveness of short-course tuberculosis preventive treatment for household contacts and people with HIV in 29 high-incidence countries: a …
T Ryckman, J Weiser, M Gombe, K Turner… - The Lancet Global …, 2023 - thelancet.com
Background Guidelines and implementation of tuberculosis preventive treatment (TPT) vary
by age and HIV status. Specifically, TPT is strongly recommended for people living with …
by age and HIV status. Specifically, TPT is strongly recommended for people living with …
Current state of the art in rapid diagnostics for antimicrobial resistance
Antimicrobial resistance (AMR) is a fundamental global concern analogous to climate
change threatening both public health and global development progress. Infections caused …
change threatening both public health and global development progress. Infections caused …
Prospective Multi-Site Validation of AI to Detect Tuberculosis and Chest X-Ray Abnormalities
Prospective Multi-Site Validation of AI to Detect Tuberculosis and Chest X-Ray
Abnormalities | NEJM AI Skip to main content NEJM AI homepage Advanced Search …
Abnormalities | NEJM AI Skip to main content NEJM AI homepage Advanced Search …
Multicomponent strategy with decentralised molecular testing for tuberculosis in Uganda: a cost and cost-effectiveness analysis
RR Thompson, T Nalugwa, D Oyuku… - The Lancet Global …, 2023 - thelancet.com
Background Decentralised molecular testing for tuberculosis could reduce missed
diagnoses and losses to follow-up in high-burden settings. The aim of this study was to …
diagnoses and losses to follow-up in high-burden settings. The aim of this study was to …
Rapid molecular tests for tuberculosis and tuberculosis drug resistance: a qualitative evidence synthesis of recipient and provider views
N Engel, EA Ochodo, PW Karanja… - Cochrane Database …, 2022 - cochranelibrary.com
Background Programmes that introduce rapid molecular tests for tuberculosis and
tuberculosis drug resistance aim to bring tests closer to the community, and thereby cut …
tuberculosis drug resistance aim to bring tests closer to the community, and thereby cut …
Cost-effectiveness of Low-complexity Screening Tests in Community-based Case-finding for Tuberculosis
LE Brümmer, RR Thompson, A Malhotra… - Clinical Infectious …, 2024 - academic.oup.com
Introduction In high-burden settings, low-complexity screening tests for tuberculosis (TB)
could expand the reach of community-based case-finding efforts. The potential costs and …
could expand the reach of community-based case-finding efforts. The potential costs and …
Xpert Ultra stool testing to diagnose tuberculosis in children in Ethiopia and Indonesia: a model-based cost-effectiveness analysis
N Mafirakureva, E Klinkenberg, I Spruijt, J Levy… - BMJ open, 2022 - bmjopen.bmj.com
Objectives The WHO currently recommends stool testing using GeneXpert MTB/Rif (Xpert)
for the diagnosis of paediatric tuberculosis (TB). The simple one-step (SOS) stool method …
for the diagnosis of paediatric tuberculosis (TB). The simple one-step (SOS) stool method …