Vaccine adjuvants: mechanisms and platforms
T Zhao, Y Cai, Y Jiang, X He, Y Wei, Y Yu… - Signal transduction and …, 2023 - nature.com
Adjuvants are indispensable components of vaccines. Despite being widely used in
vaccines, their action mechanisms are not yet clear. With a greater understanding of the …
vaccines, their action mechanisms are not yet clear. With a greater understanding of the …
The use of RNA-based treatments in the field of cancer immunotherapy
M Chehelgerdi, M Chehelgerdi - Molecular Cancer, 2023 - Springer
Over the past several decades, mRNA vaccines have evolved from a theoretical concept to a
clinical reality. These vaccines offer several advantages over traditional vaccine techniques …
clinical reality. These vaccines offer several advantages over traditional vaccine techniques …
Bioinspired and biomimetic delivery platforms for cancer vaccines
Cancer vaccines aim at eliciting tumor‐specific responses for the immune system to identify
and eradicate malignant tumor cells while sparing the normal tissues. Furthermore, cancer …
and eradicate malignant tumor cells while sparing the normal tissues. Furthermore, cancer …
The Development of Chiral Nanoparticles to Target NK Cells and CD8+ T Cells for Cancer Immunotherapy
The chirality of nanomaterials (nanoparticles, NPs) can influence their interaction with cells
and biological systems. However, how chirality can exert impact on the immune response …
and biological systems. However, how chirality can exert impact on the immune response …
Exosome-loaded degradable polymeric microcapsules for the treatment of vitreoretinal diseases
H Bao, Y Tian, H Wang, T Ye, S Wang, J Zhao… - Nature Biomedical …, 2024 - nature.com
The therapeutic benefits of many cell types involve paracrine mechanisms. Inspired by the
paracrine functions of exosomes and the sustained degradation properties of …
paracrine functions of exosomes and the sustained degradation properties of …
[HTML][HTML] Sustained delivery approaches to improving adaptive immune responses
The immune system is one of the most important, complex biological networks regulating
and protecting human health. Its precise modulation can prevent deadly infections and fight …
and protecting human health. Its precise modulation can prevent deadly infections and fight …
Polymeric nanoparticle-based nanovaccines for cancer immunotherapy
Therapeutic cancer vaccines, which are designed to amplify tumor-specific T cell responses,
have been envisioned as one of the most powerful tools for effective cancer immunotherapy …
have been envisioned as one of the most powerful tools for effective cancer immunotherapy …
[HTML][HTML] Antibody-based drug delivery systems for cancer therapy: Mechanisms, challenges, and prospects
In recent years, antibody-based cancer therapy has emerged as one of the efficient
therapeutic strategies, such as immune checkpoint inhibitors (ICIs), angiogenesis inhibitors …
therapeutic strategies, such as immune checkpoint inhibitors (ICIs), angiogenesis inhibitors …
Hematopoietic stem and progenitor cell membrane-coated vesicles for bone marrow-targeted leukaemia drug delivery
J Li, H Wu, Z Yu, Q Wang, X Zeng, W Qian, S Lu… - Nature …, 2024 - nature.com
Leukemia is a kind of hematological malignancy originating from bone marrow, which
provides essential signals for initiation, progression, and recurrence of leukemia. However …
provides essential signals for initiation, progression, and recurrence of leukemia. However …
Nanotechnology-empowered vaccine delivery for enhancing CD8+ T cells-mediated cellular immunity
After centuries of development, using vaccination to stimulate immunity has become an
effective method for prevention and treatment of a variety of diseases including infective …
effective method for prevention and treatment of a variety of diseases including infective …