[HTML][HTML] Hyperglycemia and oxidative stress: An integral, updated and critical overview of their metabolic interconnections
This review focuses on the multiple and reciprocal relationships that exist between oxidative
stress, hyperglycemia and diabetes and related metabolic disorders. Human metabolism …
stress, hyperglycemia and diabetes and related metabolic disorders. Human metabolism …
[HTML][HTML] Vascular dysfunction in preeclampsia
MA Opichka, MW Rappelt, DD Gutterman, JL Grobe… - Cells, 2021 - mdpi.com
Preeclampsia is a life-threatening pregnancy-associated cardiovascular disorder
characterized by hypertension and proteinuria at 20 weeks of gestation. Though its exact …
characterized by hypertension and proteinuria at 20 weeks of gestation. Though its exact …
Oxidative stress-induced endothelial dysfunction in cardiovascular diseases
Cardiovascular disease (CVD) is a major cause of mortality worldwide. A better
understanding of the mechanisms underlying CVD is key for better management or …
understanding of the mechanisms underlying CVD is key for better management or …
[HTML][HTML] Modulation of NRF2/KEAP1 signaling in preeclampsia
G Tossetta, S Fantone, F Piani, C Crescimanno… - Cells, 2023 - mdpi.com
Placentation is a key and tightly regulated process that ensures the normal development of
the placenta and fetal growth. Preeclampsia (PE) is a hypertensive pregnancy-related …
the placenta and fetal growth. Preeclampsia (PE) is a hypertensive pregnancy-related …
[HTML][HTML] Role of oxidative stress in the dysfunction of the placental endothelial nitric oxide synthase in preeclampsia
Preeclampsia (PE) is a multifactorial pregnancy disease, characterized by new-onset
gestational hypertension with (or without) proteinuria or end-organ failure, exclusively …
gestational hypertension with (or without) proteinuria or end-organ failure, exclusively …
[HTML][HTML] Inflammation in preeclampsia: genetic biomarkers, mechanisms, and therapeutic strategies
Y Wang, B Li, Y Zhao - Frontiers in immunology, 2022 - frontiersin.org
Objective Preeclampsia is a common and serious complication of pregnancy, posing a
threat to maternal and fetal safety due to the lack of effective biomarkers and treatment …
threat to maternal and fetal safety due to the lack of effective biomarkers and treatment …
[HTML][HTML] Gestational diabetes mellitus: the crosslink among inflammation, nitroxidative stress, intestinal microbiota and alternative therapies
ELSS de Mendonça, MBT Fragoso, JM de Oliveira… - Antioxidants, 2022 - mdpi.com
Gestational diabetes mellitus (GDM) is characterized by a set of metabolic complications
arising from adaptive failures to the pregnancy period. Estimates point to a prevalence of 3 …
arising from adaptive failures to the pregnancy period. Estimates point to a prevalence of 3 …
Expression of severe acute respiratory syndrome coronavirus 2 cell entry genes, angiotensin-converting enzyme 2 and transmembrane protease serine 2, in the …
E Bloise, J Zhang, J Nakpu, H Hamada… - American journal of …, 2021 - Elsevier
Background Although there is some evidence that severe acute respiratory syndrome
coronavirus 2 can invade the human placenta, limited data exist on the gestational age …
coronavirus 2 can invade the human placenta, limited data exist on the gestational age …
[HTML][HTML] Mechanisms of endothelial dysfunction in pre-eclampsia and gestational diabetes mellitus: windows into future cardiometabolic health?
CJ McElwain, E Tuboly, FP McCarthy… - Frontiers in …, 2020 - frontiersin.org
Placental insufficiency and adipose tissue dysregulation are postulated to play key roles in
the pathophysiology of both pre-eclampsia (PE) and gestational diabetes mellitus (GDM). A …
the pathophysiology of both pre-eclampsia (PE) and gestational diabetes mellitus (GDM). A …
[HTML][HTML] Ferritin light chain deficiency-induced ferroptosis is involved in preeclampsia pathophysiology by disturbing uterine spiral artery remodelling
X Yang, Y Ding, L Sun, M Shi, P Zhang, Z Huang… - Redox biology, 2022 - Elsevier
The proteomic analysis from samples of patients with preeclampsia (PE) displayed a low
level of ferritin light chains (FTL), but we do not know what the significance of reduced FTL in …
level of ferritin light chains (FTL), but we do not know what the significance of reduced FTL in …