Collagen is the major component of the tumor microenvironment and participates in cancer
fibrosis. Collagen biosynthesis can be regulated by cancer cells through mutated genes …

For years, the renin-angiotensin system (RAS) has been perceived as a system whose role
is to primarily modulate the functioning of the cardiovascular system. Years of research into …

The kidney flushes out toxic substances and metabolic waste products, and homeostasis is
maintained owing to the kidney efforts. Unfortunately, kidney disease is one of the illnesses …

The objective of the current study is to investigate the effect of rice bran oil (RBO) on hepatic
fibrosis as a characteristic response to persistent liver injuries. Rats were randomly allocated …

This study aimed at investigating the chemical composition and the hepatoprotective
activities of Plumbago indica L. and P. auriculata Lam. LC–MS/MS analyses for the …

Introduction: Liver tissue malfunction is a severe worldwide health concern that arises from
various chronic liver conditions. The goal of this investigation was to look into the antifibrotic …

Sansevieria species possess antioxidant and hepatoprotective activities. However, the
therapeutic potential of Sansevieria suffruticosa NE Br. in liver fibrosis was not evaluated yet …

This research investigated if pitavastatin (Pita) might protect rats' kidneys against
thioacetamide (TAA). By altering the PTEN/AKT/mTOR pathway, pitavastatin may boost …

The Angiotensin II/transforming growth factor-β1 (AngII/TGF-β1) signal axis is an important
regulatory pathway for atrial fibrosis, which can contribute to atrial fibrillation (AF). Fused in …

Aim: Adropin (ADR) is a novel regulatory polypeptide and has important effects on energy
metabolism in the heart. However, it is still unclear whether ADR can relieve ventricular …