Over the past half-century, product-related public health crises have claimed millions of
American lives. Two of these crises have been especially prominent-tobacco and opioids. In …

The fourfold increase in opioid deaths between 2000 and 2017 rivals even the COVID-19
pandemic as a health crisis for America. Why did it happen? Measures of demand for pain …

Background and Objectives: Problematic opioid use can be defined as opioid use behaviors
leading to social, medical, or psychological consequences. In some instances, people …

The devastating impact of the national opioid epidemic has given rise to hundreds of
lawsuits. This article details the extremely broad range of legal claims, compares the opioid …

The War on Drugs. What began as a battle waged on morals has created multiple public
health crises, and no recent phenomenon illustrates this in more macabre detail than …

Abstract The US Food and Drug Administration (FDA) is in crisis. FDA can hardly go a single
day without an investigation, negative news story, or scholarly critique of the agency's work …

Safe injection sites have become the next battlefield in the conflict between state and federal
drug laws. A safe injection site is a place where injection drug users can self-administer …

Background The authors estimate the probability of successful development and duration of
clinical trials for medications to treat neuropathic and nociceptive pain. The authors also …

Considering the variability in individual responses to opioids and the growing concerns
about opioid addiction, prescribing opioids for postoperative pain management after spine …

Opioid litigation continues a growing public health litigation trend in which governments
seek to hold companies responsible for population harms related to their products. The …