Neuroinflammation in acute ischemic and hemorrhagic stroke

DL Alsbrook, M Di Napoli, K Bhatia, J Biller… - Current neurology and …, 2023 - Springer
Abstract Purpose of Review This review aims to provide an overview of neuroinflammation
in ischemic and hemorrhagic stroke, including recent findings on the mechanisms and …

The role of immune cells in post-stroke angiogenesis and neuronal remodeling: the known and the unknown

Y Ma, S Yang, Q He, D Zhang, J Chang - Frontiers in immunology, 2021 - frontiersin.org
Following a cerebral ischemic event, substantial alterations in both cellular and molecular
activities occur due to ischemia-induced cerebral pathology. Mounting evidence indicates …

Stroke: Molecular mechanisms and therapies: Update on recent developments

F Shehjar, B Maktabi, ZA Rahman, GA Bahader… - Neurochemistry …, 2023 - Elsevier
Stroke, a neurological disease, is one of the leading causes of death worldwide, resulting in
long-term disability in most survivors. Annual stroke costs in the United States alone were …

Neutrophil extracellular traps: a novel target for the treatment of stroke

Z Zhao, Z Pan, S Zhang, G Ma, W Zhang, J Song… - Pharmacology & …, 2023 - Elsevier
Stroke is a threatening cerebrovascular disease caused by thrombus with high morbidity
and mortality rates. Neutrophils are the first to be recruited in the brain after stroke, which …

Neuroprotective treatments for ischemic stroke: opportunities for nanotechnology

J Kong, R Chu, Y Wang - Advanced Functional Materials, 2022 - Wiley Online Library
Stroke is one of the major causes of death and severe disability worldwide. At present,
intravenous thrombolysis to restore blood flow at the ischemic part of the brain is the main …

[HTML][HTML] Role of lipocalin 2 in stroke

RY Zhao, PJ Wei, X Sun, DH Zhang, QY He, J Liu… - Neurobiology of …, 2023 - Elsevier
Stroke is the second leading cause of death worldwide; however, the treatment choices
available to neurologists are limited in clinical practice. Lipocalin 2 (LCN2) is a secreted …

Immunothrombosis and the role of platelets in venous thromboembolic diseases

M Heestermans, G Poenou, AC Duchez… - International Journal of …, 2022 - mdpi.com
Venous thromboembolism (VTE) is the third leading cardiovascular cause of death and is
conventionally treated with anticoagulants that directly antagonize coagulation. However …

Blood-brain barrier permeability in the ischemic stroke: An update

K Mathias, RS Machado, S Stork, D Dos Santos… - Microvascular …, 2024 - Elsevier
Stroke is the second leading cause of death globally and the major cause of long-term
disability. Among the types of strokes, ischemic stroke, which occurs due to obstruction of …

Nanocarrier-based drug delivery via cell-hitchhiking: emphasizing pharmacokinetic perspective towards taming the “big-old” tumors

P Famta, S Shah, N Jain, DA Srinivasarao… - Journal of Drug Delivery …, 2023 - Elsevier
Nanocarriers (NCs) are widely explored in the development of anti-tumor therapeutics. NCs
offer many advantages over conventional drug delivery systems (DDS) such as improved …

Neutrophil extracellular traps mediated by platelet microvesicles promote thrombosis and brain injury in acute ischemic stroke

X Gao, X Zhao, J Li, C Liu, W Li, J Zhao, Z Li… - Cell Communication and …, 2024 - Springer
Abstract Aims Neutrophil extracellular traps (NETs) have been implicated in thrombotic
diseases. There is no definitive explanation for how NETs form during acute ischemic …