Intracellular Ca2+ signalling: unexpected new roles for the usual suspect

F Moccia, A Fiorio Pla, D Lim, F Lodola… - Frontiers in …, 2023 - frontiersin.org
Cytosolic Ca2+ signals are organized in complex spatial and temporal patterns that underlie
their unique ability to regulate multiple cellular functions. Changes in intracellular Ca2+ …

Recent advances in neuropeptide-related omics and gene editing: Spotlight on NPY and somatostatin and their roles in growth and food intake of fish

X Yu, H Yan, W Li - Frontiers in Endocrinology, 2022 - frontiersin.org
Feeding and growth are two closely related and important physiological processes in living
organisms. Studies in mammals have provided us with a series of characterizations of …

The effects of corticotropin-releasing factor on motor learning

E Takeuchi, T Hatanaka, T Iijima, M Kimura, A Katoh - Scientific Reports, 2024 - nature.com
Corticotropin-releasing factor (CRF) is mainly secreted from the hypothalamic
paraventricular nuclei and plays a crucial role in stress-related responses. Recent studies …

Neuropeptides and Their Roles in the Cerebellum

ZH Li, B Li, XY Zhang, JN Zhu - International Journal of Molecular …, 2024 - mdpi.com
Although more than 30 different types of neuropeptides have been identified in various cell
types and circuits of the cerebellum, their unique functions in the cerebellum remain poorly …

Transcriptional Regulation, Signaling Pathways, and Subcellular Localization of Corticotropin-Releasing Factor Receptors in the Central Nervous System

P Amado, J Zegers, HE Yarur, K Gysling - Molecular Pharmacology, 2022 - ASPET
Corticotropin-releasing factor (CRF) receptors CRF-R1 and CRF-R2 are differentially
distributed in body tissues, and although they respond differentially to stimuli due to their …

Two Signaling Modes Are Better than One: Flux-Independent Signaling by Ionotropic Glutamate Receptors Is Coming of Age

V Brunetti, T Soda, R Berra-Romani, G De Sarro… - Biomedicines, 2024 - mdpi.com
Glutamate is the major excitatory neurotransmitter in the central nervous system.
Glutamatergic transmission can be mediated by ionotropic glutamate receptors (iGluRs) …

Cerebellar granule cell

E D'Angelo - Handbook of the cerebellum and cerebellar disorders, 2021 - Springer
The cerebellar granule cells are the most numerous neurons of the brain. They are also
among those with the simplest structure by emitting just four short unbranched dendrites …

Corticotrophin-Releasing Factor Modulates the Facial Stimulation-Evoked Molecular Layer Interneuron-Purkinje Cell Synaptic Transmission in vivo in Mice

WY Wu, Y Liu, MC Wu, HW Wang, CP Chu… - Frontiers in Cellular …, 2020 - frontiersin.org
Corticotropin-releasing factor (CRF) is an important neuromodulator in central nervous
system that modulates neuronal activity via its receptors during stress responses. In …

Corticotropin-releasing factor depolarizes rat lateral vestibular nuclear neurons through activation of CRF receptors 1 and 2

Y Wang, ZP Chen, ZQ Yang, XY Zhang, JM Li, JJ Wang… - Neuropeptides, 2019 - Elsevier
Corticotropin-releasing factor (CRF) is a neuropeptide mainly synthesized in the
hypothalamic paraventricular nucleus and has been traditionally implicated in stress and …

Opposing actions of CRF-R1 and CB1 receptor on facial stimulation-induced MLI-PC plasticity in mouse cerebellar cortex

GG Li, CJ Piao, P Wan, SY Li, YX Wei, GJ Zhao… - BMC neuroscience, 2022 - Springer
Background Corticotropin-releasing factor (CRF) is the major neuromodulator orchestrating
the stress response, and is secreted by neurons in various regions of the brain. Cerebellar …