Computational Design, Synthesis, and Bioevaluation of 2-(Pyrimidin-4-yl) oxazole-4-carboxamide Derivatives: Dual Inhibition of EGFRWT and EGFRT790M with …

NR Khedkar, M Sindkhedkar, A Joseph - Bioorganic Chemistry, 2024 - Elsevier
The ongoing research in cancer treatment underscores the significance of dual epidermal
growth factor receptor (EGFR) kinase inhibitors targeting both mutant and wild-type variants …

Computational design, synthesis, and assessment of 3-(4-(4-(1, 3, 4-oxadiazol-2-yl)-1 H-imidazol-2-yl) phenyl)-1, 2, 4-oxadiazole derivatives as effective epidermal …

NR Khedkar, M Sindkhedkar, A Joseph - RSC Medicinal Chemistry, 2024 - pubs.rsc.org
The epidermal growth factor receptor (EGFR) enzyme plays a critical role in governing the
cell cycle, positioning it as a promising target for the development of anticancer drugs. In this …