The next phase of SARS-CoV-2 surveillance: real-time molecular epidemiology
The current coronavirus disease 2019 (COVID-19) pandemic is the first to apply whole-
genome sequencing near to real time, with over 2 million severe acute respiratory syndrome …
genome sequencing near to real time, with over 2 million severe acute respiratory syndrome …
Advancing lung organoids for COVID-19 research
J van der Vaart, MM Lamers… - Disease Models & …, 2021 - journals.biologists.com
The COVID-19 pandemic has emphasised the need to develop effective treatments to
combat emerging viruses. Model systems that poorly represent a virus' cellular environment …
combat emerging viruses. Model systems that poorly represent a virus' cellular environment …
SARS-CoV-2 variant Alpha has a spike-dependent replication advantage over the ancestral B. 1 strain in human cells with low ACE2 expression
D Niemeyer, S Stenzel, T Veith, S Schroeder… - PLoS …, 2022 - journals.plos.org
Epidemiological data demonstrate that Severe Acute Respiratory Syndrome Coronavirus 2
(SARS-CoV-2) variants of concern (VOCs) Alpha and Delta are more transmissible …
(SARS-CoV-2) variants of concern (VOCs) Alpha and Delta are more transmissible …
Niclosamide shows strong antiviral activity in a human airway model of SARS-CoV-2 infection and a conserved potency against the Alpha (B. 1.1. 7), Beta (B. 1.351) …
SARS-CoV-2 variants are emerging with potential increased transmissibility highlighting the
great unmet medical need for new therapies. Niclosamide is a potent anti-SARS-CoV-2 …
great unmet medical need for new therapies. Niclosamide is a potent anti-SARS-CoV-2 …
[HTML][HTML] Bioengineered Co-culture of organoids to recapitulate host-microbe interactions
The recent spike in the instances of complex physiological host-microbe interactions has
raised the demand for developing in vitro models that recapitulate the microbial …
raised the demand for developing in vitro models that recapitulate the microbial …
Emerging SARS-CoV-2 genotypes show different replication patterns in human pulmonary and intestinal epithelial cells
GAP de Souza, M Le Bideau, C Boschi, L Ferreira… - Viruses, 2021 - mdpi.com
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) quickly spread
worldwide following its emergence in Wuhan, China, and hit pandemic levels. Its …
worldwide following its emergence in Wuhan, China, and hit pandemic levels. Its …
Organoid Models of SARS-CoV-2 infection: what have we learned about COVID-19?
BM Tran, G Deliyannis, A Hachani, L Earnest, J Torresi… - Organoids, 2022 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus
disease 2019 (COVID-19), which was classified as a pandemic in March 2020. As of 22 …
disease 2019 (COVID-19), which was classified as a pandemic in March 2020. As of 22 …
Pulmonary lesions following inoculation with the SARS-CoV-2 Omicron BA. 1 (B. 1.1. 529) variant in Syrian golden hamsters
M Rissmann, D Noack, D van Riel… - Emerging Microbes & …, 2022 - Taylor & Francis
ABSTRACT The Omicron BA. 1 (B. 1.1. 529) SARS-CoV-2 variant is characterized by a high
number of mutations in the viral genome, associated with immune escape and increased …
number of mutations in the viral genome, associated with immune escape and increased …
Airway models in a pandemic: Suitability of models in modeling SARS-CoV-2
A Teo, CLL Chua, LLY Chan - PLoS Pathogens, 2022 - journals.plos.org
In a global pandemic involving respiratory pathogens such as Severe Acute Respiratory
Syndrome Coronavirus 2 (SARS-CoVAU: PleasenotethatSARS À CoV À 2hasbeendefinedasSevereAcuteRespirator …
Syndrome Coronavirus 2 (SARS-CoVAU: PleasenotethatSARS À CoV À 2hasbeendefinedasSevereAcuteRespirator …
Post-entry, spike-dependent replication advantage of B. 1.1. 7 and B. 1.617. 2 over B. 1 SARS-CoV-2 in an ACE2-deficient human lung cell line
D Niemeyer, S Schroeder, K Friedmann, F Weege… - bioRxiv, 2021 - biorxiv.org
Epidemiological data demonstrate that SARS-CoV-2 variants of concern (VOC) B. 1.1. 7 and
B. 1.617. 2 are more transmissible and infections are associated with a higher mortality than …
B. 1.617. 2 are more transmissible and infections are associated with a higher mortality than …