Neutrophils are frontline cells of the innate immune system. These effector leukocytes are
equipped with intriguing antimicrobial machinery and consequently display high cytotoxic …

Neutrophils are best known for their critical role in host defense, for which they utilize
multiple innate immune mechanisms, including microbe-associated pattern recognition …

Neutrophils are the most abundant innate immune cells. The pathogenic roles of neutrophils
are related to chronic inflammation and autoimmune diseases. Psoriasis is a chronic …

Neutrophils, the most abundant white blood cells in humans, are critical for host defense
against invading pathogens. Equipped with an array of antimicrobial molecules, neutrophils …

Neutrophils are the most abundant immune cell type in the blood and constitute the first line
of defense against invading pathogens. Despite their important role in many diseases, they …

Neutrophil granulocytes form the first line of host defense against invading pathogens and
tissue injury. They are rapidly recruited from the blood to the affected sites, where they …

Rheumatoid arthritis (RA), a common autoimmune disease, is characterized by a highly
coordinated inflammatory response that involves innate and adaptive immunity. One of the …

Vascular pathologies underpin and intertwine autoimmune rheumatic diseases and
cardiovascular conditions, and atherosclerosis is increasingly recognized as the leading …

Autophagy is an evolutionarily conserved intracellular degradation system aiming to
maintain cell homeostasis in response to cellular stress. At physiological states, basal or …

Several studies have indicated that a neutrophil extracellular trap (NET) formation, apart
from its role in host defense, can contribute to or drive pathogenesis in a wide range of …