Synthetic approaches and pharmacological activity of 1, 3, 4-oxadiazoles: a review of the literature from 2000–2012

CS De Oliveira, BF Lira, JM Barbosa-Filho… - Molecules, 2012 - mdpi.com
Molecules | Free Full-Text | Synthetic Approaches and Pharmacological Activity of 1,3,4-Oxadiazoles:
A Review of the Literature from 2000–2012 Next Article in Journal Chemical Composition of …

1, 3, 4-Oxadiazole: A privileged structure in antiviral agents

Z Li, P Zhan, X Liu - Mini Reviews in Medicinal Chemistry, 2011 - ingentaconnect.com
1, 3, 4-oxadiazole, a privileged structure, endows its derivatives with broad and potent
biological functions, especially in antiviral activities, including anti-HIV, anti-HCV, anti-HBV …

Synthesis, crystal structures, computational studies and antimicrobial activity of new designed bis ((5-aryl-1, 3, 4-oxadiazol-2-yl) thio) alkanes

MN Ahmed, B Sadiq, NA Al-Masoudi, KA Yasin… - Journal of Molecular …, 2018 - Elsevier
A new series of bis ((5-aryl-1, 3, 4-oxadiazol-2-yl) thio) alkanes 4–14 have been synthesized
via nucleophilic substitution reaction of dihaloalkanes with respective 1, 3, 4-oxadiazole-2 …

Design and synthesis of novel 1, 3, 4‐oxadiazole based azaspirocycles catalyzed by NaI under mild condition and evaluated their antidiabetic and antibacterial …

AJ Radia, JN Lalpara, IJ Modasiya… - Journal of Heterocyclic …, 2021 - Wiley Online Library
A modest, efficient, and mild synthetic procedure has been developed for the synthesis of
novel series of 1, 3, 4‐oxadiazole containing azaspirocycles derivatives. The reaction of 1, 3 …

Synthesis, Molecular Properties Prediction, and Anti-staphylococcal Activity of N-Acylhydrazones and New 1,3,4-Oxadiazole Derivatives

CS De Oliveira, BF Lira, V dos Santos Falcão-Silva… - Molecules, 2012 - mdpi.com
Five new 1-(2-(5-nitrofuran-2-yl)-5-(aryl)-1, 3, 4-oxadiazol-3-(2 H)-yl) ethanone compounds
5a–e were synthesized by cyclization of N-acylhydrazones 4a–e with acetic anhydride …

Metal-and solvent-free synthesis of N-sulfonylformamidines

N Chandna, N Chandak, P Kumar, JK Kapoor… - Green chemistry, 2013 - pubs.rsc.org
A solvent-free green synthesis of N-sulfonylformamidines is reported via the direct
condensation of N, N-dimethylformamide dimethyl acetal (DMF-DMA) and sulfonamide …

4-Amino-substituted Benzenesulfonamides as Inhibitors of Human Carbonic Anhydrases

K Rutkauskas, A Zubrienė, I Tumosienė, K Kantminienė… - Molecules, 2014 - mdpi.com
A series of N-aryl-β-alanine derivatives and diazobenzenesulfonamides containing aliphatic
rings were designed, synthesized, and their binding to carbonic anhydrases (CA) I, II, VI, VII …

Exploration of antimicrobial potential of pyrazolo[3,4-b]pyridine scaffold bearing benzenesulfonamide and trifluoromethyl moieties

N Chandak, S Kumar, P Kumar, C Sharma… - Medicinal Chemistry …, 2013 - Springer
The synthesis and biological evaluation of a library of thirty differently substituted pyrazolo
[3, 4-b] pyridines bearing benzenesulfonamide moiety at position-1 and trifluoromethyl …

Synthesis of some new benzisothiazolone and benzenesulfonamide derivatives of biological interest starting from saccharin sodium

OI El‐Sabbagh - Archiv der Pharmazie, 2013 - Wiley Online Library
Two new series of benzenesulfonamide (4a–f, 5a–b, 6, 7) and 1, 2‐benzisothiazol‐3 (2H)‐
one‐1, 1‐dioxide (9a–c, 10, 12a–d) derivatives were prepared starting from saccharin …

Oxadiazole-an important bioactive scaffold for drug discovery and development process against HIV and cancer-a review

D Kumar, V Kumar, R Marwaha… - Current Bioactive …, 2019 - ingentaconnect.com
Background: Acquired immunodeficiency syndrome (AIDS) and cancer treatment have been
a major task for research scientists and pharmaceutical industry for the last many years …