The prevalence of obesity has tripled over the past four decades, imposing an enormous
burden on people's health. Polygenic (or common) obesity and rare, severe, early-onset …

Polycystic ovary syndrome (PCOS) is among the most common disorders in women of
reproductive age, affecting up to 15% worldwide, depending on the diagnostic criteria …

Severe obesity is a rapidly growing global health threat. Although often attributed to
unhealthy lifestyle choices or environmental factors, obesity is known to be heritable and …

Genome-wide association studies (GWAS) for BMI, waist-to-hip ratio, and other adiposity
traits have identified more than 300 single-nucleotide polymorphisms (SNPs). Although …

Objectives. To review the contribution of the Nurses' Health Studies (NHS and NHS II) in
addressing hypotheses regarding risk factors for and consequences of obesity. Methods …

Obesity and diabetes mellitus have reached epidemic proportions in the past few years.
During 2011 to 2012, more than one-third of the US population was obese. Although recent …

The translation of the growing increase of findings emerging from basic nutritional science
into meaningful and clinically relevant dietary advices represents nowadays one of the main …

Aims To investigate whether metabolic signature composed of multiple plasma metabolites
can be used to characterize adherence and metabolic response to the Mediterranean diet …

Background Obesity is a global health problem mainly attributed to lifestyle changes such as
diet, low physical activity or socioeconomics factors. However, several evidences …

Genetic predisposition to obesity presents a paradox: how do genetic variants with a
detrimental impact on human health persist through evolutionary time? Numerous …