Pathogenesis and virulence of Candida albicans

JP Lopes, MS Lionakis - Virulence, 2022 - Taylor & Francis
Candida albicans is a commensal yeast fungus of the human oral, gastrointestinal, and
genital mucosal surfaces, and skin. Antibiotic-induced dysbiosis, iatrogenic …

The impact of the Fungus-Host-Microbiota interplay upon Candida albicans infections: current knowledge and new perspectives

C d'Enfert, AK Kaune, LR Alaban… - FEMS microbiology …, 2021 - academic.oup.com
Candida albicans is a major fungal pathogen of humans. It exists as a commensal in the oral
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …

[HTML][HTML] Invasive candidiasis

PG Pappas, MS Lionakis, MC Arendrup… - Nature Reviews …, 2018 - nature.com
Invasive candidiasis is an important health-care-associated fungal infection that can be
caused by several Candida spp.; the most common species is Candida albicans, but the …

Interactions of fungal pathogens with phagocytes

LP Erwig, NAR Gow - Nature Reviews Microbiology, 2016 - nature.com
The surveillance and elimination of fungal pathogens rely heavily on the sentinel behaviour
of phagocytic cells of the innate immune system, especially macrophages and neutrophils …

Commensal fungi recapitulate the protective benefits of intestinal bacteria

TT Jiang, TY Shao, WXG Ang, JM Kinder, LH Turner… - Cell host & …, 2017 - cell.com
Commensal intestinal microbes are collectively beneficial in preventing local tissue injury
and augmenting systemic antimicrobial immunity. However, given the near-exclusive focus …

Innate immune responses against the fungal pathogen Candida auris

Y Wang, Y Zou, X Chen, H Li, Z Yin, B Zhang… - Nature …, 2022 - nature.com
Candida auris is a multidrug-resistant human fungal pathogen responsible for nosocomial
outbreaks worldwide. Although considerable progress has increased our understanding of …

Candida albicans morphogenesis and host defence: discriminating invasion from colonization

NAR Gow, FL Van De Veerdonk, AJP Brown… - Nature reviews …, 2012 - nature.com
Candida albicans is a common fungal pathogen of humans that colonizes the skin and
mucosal surfaces of most healthy individuals. Until recently, little was known about the …

Forgotten fungi—the gut mycobiome in human health and disease

CE Huseyin, PW O'Toole, PD Cotter… - FEMS Microbiology …, 2017 - academic.oup.com
The human body is home to a complex and diverse microbial ecosystem that plays a central
role in host health. This includes a diversity of fungal species that is collectively referred to …

Regulation of host-microbe interactions at oral mucosal barriers by type 17 immunity

SL Gaffen, NM Moutsopoulos - Science immunology, 2020 - science.org
The oral mucosa is a primary barrier site and a portal for entry of microbes, food, and
airborne particles into the gastrointestinal tract. Nonetheless, mucosal immunity at this …

STAT1 Mutations in Autosomal Dominant Chronic Mucocutaneous Candidiasis

FL van de Veerdonk, TS Plantinga… - … England Journal of …, 2011 - Mass Medical Soc
Background Chronic mucocutaneous candidiasis (CMC) is characterized by susceptibility to
candida infection of skin, nails, and mucous membranes. Patients with recessive CMC and …