Brain oxytocin: how puzzle stones from animal studies translate into psychiatry

V Grinevich, ID Neumann - Molecular psychiatry, 2021 - nature.com
The neuropeptide oxytocin has attracted great attention of the general public, basic
neuroscience researchers, psychologists, and psychiatrists due to its profound pro-social …

Oxytocin and the neurobiology of prosocial behavior

N Marsh, AA Marsh, MR Lee… - The …, 2021 - journals.sagepub.com
Humans are an unusually prosocial species, who engage in social behaviors that include
altruism—whereby an individual engages in costly or risky acts to improve the welfare of …

Neuropeptide Y is an immunomodulatory factor: direct and indirect

W Chen, Y Liu, W Liu, Y Zhou, H He, S Lin - Frontiers in immunology, 2020 - frontiersin.org
Neuropeptide Y (NPY), which is widely distributed in the nervous system, is involved in
regulating a variety of biological processes, including food intake, energy metabolism, and …

Chronic oxytocin-driven alternative splicing of Crfr2α induces anxiety

J Winter, M Meyer, I Berger, M Royer, M Bianchi… - Molecular …, 2023 - nature.com
The neuropeptide oxytocin (OXT) has generated considerable interest as potential treatment
for psychiatric disorders, including anxiety and autism spectrum disorders. However, the …

Structure-function relationships of the disease-linked A218T oxytocin receptor variant

M Meyer, B Jurek, M Alfonso-Prieto, R Ribeiro… - Molecular …, 2022 - nature.com
Various single nucleotide polymorphisms (SNPs) in the oxytocin receptor (OXTR) gene have
been associated with behavioral traits, autism spectrum disorder (ASD) and other diseases …

The modulation of emotional and social behaviors by oxytocin signaling in limbic network

R Triana-Del Rio, S Ranade, J Guardado… - Frontiers in Molecular …, 2022 - frontiersin.org
Neuropeptides can exert volume modulation in neuronal networks, which account for a well-
calibrated and fine-tuned regulation that depends on the sensory and behavioral contexts …

[HTML][HTML] Molecular, biochemical and behavioural evidence for a novel oxytocin receptor and serotonin 2C receptor heterocomplex

B Chruścicka, CSM Cowan, SEW Fitzsimons… - …, 2021 - Elsevier
The complexity of oxytocin-mediated functions is strongly associated with its modulatory
effects on other neurotransmission systems, including the serotonin (5-hydroxytryptamine, 5 …

Anxiolytic and anxiogenic? How the transcription factor MEF2 might explain the manifold behavioral effects of oxytocin

B Jurek, M Meyer - Frontiers in endocrinology, 2020 - frontiersin.org
The neuromodulator oxytocin, since its first synthesis by du Vigneaud in 1953, has mainly
been associated with beneficial physiological effects, as well as positive social and …

Central and peripheral release of oxytocin: Relevance of neuroendocrine and neurotransmitter actions for physiology and behavior

F Althammer, M Eliava, V Grinevich - Handbook of clinical neurology, 2021 - Elsevier
The hypothalamic neuropeptide oxytocin (OT) is critically involved in the modulation of socio-
emotional behavior, sexual competence, and pain perception and anticipation. While …

Cataloguing and selection of mRNAs localized to dendrites in neurons and regulated by RNA-binding proteins in RNA granules

R Ohashi, N Shiina - Biomolecules, 2020 - mdpi.com
Spatiotemporal translational regulation plays a key role in determining cell fate and function.
Specifically, in neurons, local translation in dendrites is essential for synaptic plasticity and …