Rice brans, rice bran oils, and rice hulls: composition, food and industrial uses, and bioactivities in humans, animals, and cells

M Friedman - Journal of agricultural and food chemistry, 2013 - ACS Publications
Rice plants produce bioactive rice brans and hulls that have been reported to have
numerous health-promoting effects in cells, animals, and humans. The main objective of this …

Potential role of tocotrienols on non-communicable diseases: a review of current evidence

SK Wong, Y Kamisah, N Mohamed, N Muhammad… - Nutrients, 2020 - mdpi.com
Tocotrienol (T3) is a subfamily of vitamin E known for its wide array of medicinal properties.
This review aimed to summarize the health benefits of T3, particularly in prevention or …

Mitochondrial Oxidative Stress Impairs Energy Metabolism and Reduces Stress Resistance and Longevity of C. elegans

B Dilberger, S Baumanns, F Schmitt… - Oxidative medicine …, 2019 - Wiley Online Library
Introduction. Mitochondria supply cellular energy and are key regulators of intrinsic cell
death and consequently affect longevity. The nematode Caenorhabditis elegans is …

Curcumin micelles improve mitochondrial function in neuronal PC12 cells and brains of NMRI mice–Impact on bioavailability

S Hagl, A Kocher, C Schiborr, N Kolesova… - Neurochemistry …, 2015 - Elsevier
Curcumin, a polyphenolic compound abundant in the rhizome of Curcuma longa, has been
reported to have various beneficial biological and pharmacological activities. Recent …

Omega-3 polyunsaturated fatty acids improve mitochondrial dysfunction in brain aging–impact of Bcl-2 and NPD-1 like metabolites

S Afshordel, S Hagl, D Werner, N Röhner… - … and Essential Fatty …, 2015 - Elsevier
The present study investigated the effects of orally administered long chain omega-3
polyunsaturated fatty acids (PUFA) on mitochondrial function and processing of the amyloid …

Cerebral mitochondrial function and cognitive performance during aging: a longitudinal study in NMRI mice

M Reutzel, R Grewal, B Dilberger… - Oxidative medicine …, 2020 - Wiley Online Library
Brain aging is one of the major risk factors for the development of several
neurodegenerative diseases. Therefore, mitochondrial dysfunction plays an important role in …

[HTML][HTML] Rice bran, an off-shoot to newer therapeutics in neurological disorders

T Behl, S Kumar, A Sehgal, S Singh, S Kumari… - Biomedicine & …, 2021 - Elsevier
Normal brain functioning involves the interaction of interconnected molecular and cellular
activities, which appear to alter normal to abnormal brain functioning when worsened …

Ferulic acid, a bioactive component of rice bran, improves oxidative stress and mitochondrial biogenesis and dynamics in mice and in human mononuclear cells

C Perez-Ternero, CM Werner, AG Nickel… - The Journal of …, 2017 - Elsevier
The aim of the study was to characterize the vascular effects of rice bran enzymatic extract
(RBEE). ApoE−/− mice were fed a high-fat/cholesterol diet (HFD) or HFD supplemented with …

Rice bran derivatives alleviate microglia activation: possible involvement of MAPK pathway

HS Bhatia, J Baron, S Hagl, GP Eckert… - Journal of …, 2016 - Springer
Background Hyperactivation of microglia is considered to be a key hallmark of brain
inflammation and plays a critical role in regulating neuroinflammatory events …

Potential health benefits of whole grains: modulation of mitochondrial biogenesis and energy metabolism

Z Wang, Z Yang, J Liu, Y Hao, B Sun… - Journal of Agricultural …, 2021 - ACS Publications
Mitochondria play an essential role in maintaining cellular metabolic homeostasis. However,
its dysfunction will cause different pathophysiological consequences. A specific mechanism …