Homology modeling, virtual screening, molecular docking, molecular dynamic (MD) simulation, and ADMET approaches for identification of natural anti-Parkinson …
Abstract Monoamine oxidase-B (MAO-B) is a flavin-dependent enzyme involved in various
neurodegenerative disorders. Here, a dataset of 142 chalcone derivatives, collected from …
neurodegenerative disorders. Here, a dataset of 142 chalcone derivatives, collected from …
[PDF][PDF] Synthesis and biological evaluation of some new pyrimidines via a novel chalcone series
AR Trivedi, DK Dodiya, NR Ravat, VH Shah - Arkivoc, 2008 - arkat-usa.org
In the present investigation ethyl 2-(4-carboxyphenylazo) acetoacetate 1 on condensation
with various aromatic aldehydes in ethanolic NaOH solution yielded the corresponding …
with various aromatic aldehydes in ethanolic NaOH solution yielded the corresponding …
Structure-based virtual screening of novel natural products as chalcone derivatives against SARS-CoV-2 Mpro
A El Aissouq, M Bouachrine, L Bouayyadi… - Journal of …, 2023 - Taylor & Francis
Abstract Coronavirus disease 2019 (COVID-19), which is caused by SARS-CoV-2, has
spread quickly around the world, causing a global pandemic. It has infected more than 500 …
spread quickly around the world, causing a global pandemic. It has infected more than 500 …
Synthesis and biological activities of N-alkyl derivatives of o-, m-, and p-nitro (E)-4-azachalcones and stereoselective photochemistry in solution, with theoretical …
The N-alkyl derivatisation and photochemical dimerisation of 3 o-, m-, and p-nitro substituted
4-azachalcones (1-3) yielded 3 new o-, m-, and p-nitro substituted (E)-N-decyl-4 …
4-azachalcones (1-3) yielded 3 new o-, m-, and p-nitro substituted (E)-N-decyl-4 …
Synthesis and antimycobacterial activity of novel heterocycles
In the present investigation 4-hydroxy-3-methylacetophenone on condensation with various
aromatic aldehydes in methanolic KOH solution yielded the corresponding chalcones (CI …
aromatic aldehydes in methanolic KOH solution yielded the corresponding chalcones (CI …
Synthesis, anti-inflammatory activity and ulcerogenic liability of novel nitric oxide donating/chalcone hybrids
GEDAA Abuo-Rahma, M Abdel-Aziz… - Bioorganic & medicinal …, 2012 - Elsevier
A group of novel nitric oxide (NO) donating chalcone derivatives was prepared by binding
various amino chalcones with different NO donating moieties including; nitrate ester, oximes …
various amino chalcones with different NO donating moieties including; nitrate ester, oximes …
[PDF][PDF] Synthesis and characterization of some chalcones and their cyclohexenone derivatives
TV Sreevidya, B Narayana… - Central European Journal …, 2010 - academia.edu
A series of chalcones and their derivatives have been synthesized. Chalcones, 1-(1, 3-
benzodioxol-5-yl)-3-(aryl)-prop-2-en-1-ones were prepared by the aldol condensation of 1 …
benzodioxol-5-yl)-3-(aryl)-prop-2-en-1-ones were prepared by the aldol condensation of 1 …
Combinatorial Synthesis, Lead Identification, and Antitumor Study of a Chalcone‐Based Positional‐Scanning Library
A 175‐member chalcone library was designed and synthesized from seven differently
substituted acetophenones (A1–A7) and 25 differently substituted aryl or heteroaryl …
substituted acetophenones (A1–A7) and 25 differently substituted aryl or heteroaryl …
[HTML][HTML] Photogeneration of reactive oxygen species and photoinduced plasmid DNA cleavage by novel synthetic chalcones
Y Yesuthangam, S Pandian, K Venkatesan… - … of Photochemistry and …, 2011 - Elsevier
This paper describes the synthesis and photodynamic properties of six different chalcone
derivatives. Using N, N-dimethyl-4-nitrosoaniline (RNO) bleaching assay, the singlet oxygen …
derivatives. Using N, N-dimethyl-4-nitrosoaniline (RNO) bleaching assay, the singlet oxygen …
Synthesis and preliminary evaluation of several chalcone derivatives as sunscreen compounds
J Jumina, RW Styaningrum, D Siswanta… - Chemistry Journal of …, 2019 - ibn.idsi.md
Four chalcone derivatives containing chloro and methoxy substituents were synthesized and
pre-evaluated as broad-spectrum UV protector with intrinsic antioxidant activity. UV …
pre-evaluated as broad-spectrum UV protector with intrinsic antioxidant activity. UV …